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Ch. 5 The Integumentary System
Marieb - Human Anatomy & Physiology 11th Edition
Marieb, Hoehn11th EditionHuman Anatomy & PhysiologyISBN: 9780136874034Non è quello che usi tu?Cambia libro di testo
Tutti i libri di testoMarieb, Hoehn 11th EditionCh. 5 The Integumentary SystemProblema 14
Capitolo 5, Problema 14

Which epidermal cells contain keratohyaline and lamellar granules?

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Understand that the epidermis is composed of several layers of cells, each with distinct functions and characteristics.
Recall that keratohyaline granules are involved in the process of keratinization, helping to form the dense protein matrix in the skin's outer layer.
Recognize that lamellar granules contain lipids that contribute to the skin's waterproof barrier by filling spaces between cells.
Identify the specific epidermal cell type that contains both keratohyaline and lamellar granules; these are the cells in the stratum granulosum layer.
Conclude that the keratinocytes in the stratum granulosum are the epidermal cells containing keratohyaline and lamellar granules, playing a key role in skin barrier formation.

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Epidermal Cell Types

The epidermis consists of several cell types, including keratinocytes, melanocytes, Langerhans cells, and Merkel cells. Keratinocytes are the most abundant and are responsible for producing keratin and other granules essential for skin barrier function.
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Other Epidermal Cells

Keratohyaline Granules

Keratohyaline granules are dense, protein-rich structures found in the granular layer of keratinocytes. They contain profilaggrin, which helps in the aggregation of keratin filaments, contributing to the formation of the skin’s protective outer layer.
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Granulocytes

Lamellar Granules

Lamellar granules are lipid-containing organelles in keratinocytes that release lipids into the extracellular space. These lipids form a waterproof barrier, preventing water loss and protecting the skin from external environmental damage.
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Structure of Lamellae
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Which is not a true statement about the papillary dermis?

a. It is largely areolar connective tissue

b. It is most responsible for the toughness of the skin

c. It contains nerve endings that respond to stimuli

d. It is highly vascular

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The rule of nines is helpful clinically in

a. Diagnosing skin cancer

b. Estimating the extent of a burn

c. Estimating how serious a cancer is

d. Preventing acne

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Why are there no skin cancers that originate from stratum corneum cells?

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Which of the following is not an epidermal derivative?

a. Hair

b. Sweat gland

c. Sensory receptor

d. Sebaceous gland.

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Explain each of these familiar phenomena in terms of what you learned in this chapter:

a. Pimples

b. Dandruff

c. Greasy hair and 'shiny nose

d. Stretch marks from gaining weight

e. Freckles

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Count Dracula, the most famous vampire, rumored to have killed at least 200,000 people, was based on a real person who lived in eastern Europe about 600 years ago. He was indeed a “monster,” although he was not a real vampire. The historical Count Dracula may have suffered from which of the following?

(a) Porphyria

(b) EB

(c) Halitosis

(d) Vitiligo

Explain your answer.

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