Patty, aged 55, is awakened by excruciating pain that radiates from her right abdomen to the loin and groin regions on the same side. The pain is not continuous but recurs at intervals of 3 to 4 minutes. Diagnose her problem, and cite factors that might favor its occurrence.

Why are renal failure patients undergoing dialysis at risk for anemia and osteoporosis? What medications or supplements could you give them to prevent these problems?

While repairing a frayed utility wire, Kevin, an experienced lineman, slips and falls to the ground. Medical examination reveals a fracture of his lower spine and transection of the lumbar region of the spinal cord. How will Kevin's micturition be controlled from this point on? Will he ever again feel the need to void? Will there be dribbling of urine between voidings? Explain the reasoning behind all your responses.

Mrs. Bigda, a 60-year-old woman, was brought to the hospital by the police after falling to the pavement. She is found to have alcoholic hepatitis. She is put on a salt- and protein-restricted diet and diuretics are prescribed to manage her ascites (accumulated fluid in the peritoneal cavity). How will diuretics reduce this excess fluid? Name and describe the mechanisms of action of three types of diuretics. Why is her diet salt-restricted?

Explain why the filtrate becomes hypotonic as it flows through the ascending limb of the nephron loop. Also explain why the filtrate at the bend of the nephron loop (and the interstitial fluid of the deep portions of the medulla) is hypertonic.