describe-the-role-of-guanine-exchange-factors-gefs-like-saws-in-the-activation-o

Question

Describe the role of guanine exchange factors (GEFs) like SAWS in the activation of RAS.

Accepted Answer

GEFs promote the exchange of GDP for GTP on RAS, activating it for downstream signaling.

Answer

GEFs phosphorylate RAS, activating it for downstream signaling.

Answer

GEFs degrade RAS, terminating the signal.

Answer

GEFs inhibit the exchange of GDP for GTP on RAS, preventing its activation.