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What advantage do individuals with one sickle cell allele have?
A
Higher fertility rates
B
Improved oxygen transport in blood
C
Enhanced physical endurance
D
Increased resistance to malaria
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1
Understand the genetic basis of sickle cell disease: It is caused by a mutation in the hemoglobin gene, resulting in sickle-shaped red blood cells.
Recognize that individuals with one sickle cell allele (heterozygotes) have a condition known as sickle cell trait, which usually does not cause severe symptoms.
Learn about malaria: It is a disease caused by Plasmodium parasites, transmitted through the bites of infected mosquitoes, and it affects red blood cells.
Explore the relationship between sickle cell trait and malaria: The presence of one sickle cell allele provides a protective advantage against malaria, as the altered shape of red blood cells makes it harder for the malaria parasite to thrive.
Conclude that individuals with one sickle cell allele have increased resistance to malaria, which is an evolutionary advantage in regions where malaria is prevalent.