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During which phase of mitosis do sister chromatids align along the center (equator) of the cell?
A
Telophase
B
Prophase
C
Metaphase
D
Anaphase
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1
Understand the process of mitosis, which is the division of a cell's nucleus into two identical nuclei. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that sister chromatids are identical copies of a chromosome that are connected by a centromere. These chromatids are separated during mitosis to ensure each daughter cell receives an identical set of chromosomes.
Focus on the metaphase stage of mitosis. During metaphase, the sister chromatids align along the metaphase plate, which is the center (equator) of the cell. This alignment ensures proper segregation of chromosomes during the next phase.
Compare metaphase to other phases of mitosis: In prophase, chromosomes condense and the nuclear envelope breaks down; in anaphase, sister chromatids are pulled apart to opposite poles of the cell; in telophase, the nuclear envelope reforms around the separated chromosomes.
Conclude that the correct phase during which sister chromatids align along the center of the cell is metaphase, as this is the defining characteristic of this stage in mitosis.