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During which phase of mitosis do the chromosomes align at the middle part of the cell?
A
Telophase
B
Anaphase
C
Metaphase
D
Prophase
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1
Understand the process of mitosis, which is the division of a cell's nucleus into two identical nuclei. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during metaphase, chromosomes align at the metaphase plate, which is the middle part of the cell. This alignment ensures that each daughter cell will receive an identical set of chromosomes.
Review the role of spindle fibers during metaphase. Spindle fibers attach to the centromeres of the chromosomes and help position them at the metaphase plate.
Differentiate metaphase from other phases of mitosis: In prophase, chromosomes condense and spindle fibers begin to form; in anaphase, sister chromatids are pulled apart; and in telophase, the nuclear envelope reforms around the separated chromatids.
Conclude that the correct phase during which chromosomes align at the middle part of the cell is metaphase, as this is the defining characteristic of this stage in mitosis.