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Which is an accurate statement regarding the difference between steroid and nonsteroid hormones?
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43. Endocrine System
Endocrine System
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Which of the following hormones is thought to act at the cellular level by inducing a change in gene expression?
A
Prostaglandin
B
Prothoracicotropic hormone (PTTH)
C
Nitric oxide
D
Epinephrine
E
Estrogen
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Understand that hormones can exert their effects by binding to receptors either on the cell surface or inside the cell, leading to different types of cellular responses.
Recognize that steroid hormones, like estrogen, are lipid-soluble and can pass through the cell membrane to bind to intracellular receptors.
Once inside the cell, estrogen binds to its specific receptor, forming a hormone-receptor complex.
This hormone-receptor complex then translocates to the cell nucleus, where it can bind to specific DNA sequences, acting as a transcription factor.
By binding to DNA, the hormone-receptor complex can regulate the transcription of specific genes, thereby inducing changes in gene expression at the cellular level.
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