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During which phase of mitosis do sister chromatids line up along the equator (metaphase plate) of the cell?
A
Prophase
B
Metaphase
C
Anaphase
D
Telophase
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Understand the question: The problem is asking about the specific phase of mitosis during which sister chromatids align along the equator (metaphase plate) of the cell.
Recall the key events of mitosis: Mitosis is divided into four main phases: Prophase, Metaphase, Anaphase, and Telophase. Each phase has distinct characteristics.
Focus on Metaphase: During Metaphase, the sister chromatids are aligned at the cell's equator, also known as the metaphase plate. This alignment is facilitated by the spindle fibers attaching to the centromeres of the chromatids.
Compare with other phases: In Prophase, chromosomes condense and spindle fibers begin to form. In Anaphase, sister chromatids are pulled apart to opposite poles of the cell. In Telophase, the chromosomes decondense, and the nuclear envelope reforms. None of these phases involve the alignment of chromatids at the equator.
Conclude: Based on the characteristics of each phase, the correct answer is Metaphase, as this is when sister chromatids line up along the metaphase plate.