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What is the DNA sequence that serves as the template for synthesizing the mRNA sequence 5'-AUGGCUAAC-3'?
A
5'-ATGGCATTC-3'
B
3'-TACCGATTG-5'
C
3'-UACCGUAAC-5'
D
5'-TACCGTAAC-3'
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1
Understand that mRNA is synthesized from a DNA template strand during transcription. The mRNA sequence is complementary to the DNA template strand.
Identify the directionality of the mRNA sequence given: 5'-AUGGCUAAC-3'. This sequence is synthesized in the 5' to 3' direction.
Recall that the DNA template strand is complementary to the mRNA sequence and runs in the opposite direction, 3' to 5'.
Use base pairing rules to determine the DNA template sequence: Adenine (A) pairs with Thymine (T), Uracil (U) in RNA pairs with Adenine (A) in DNA, Cytosine (C) pairs with Guanine (G), and Guanine (G) pairs with Cytosine (C).
Write the complementary DNA template strand in the 3' to 5' direction based on the mRNA sequence: 3'-TACCGATTG-5'.