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Why do histones bind tightly to DNA?
A
Because histones are hydrophobic and DNA is hydrophilic.
B
Because histones are composed of RNA, which naturally binds to DNA.
C
Because histones are positively charged and DNA is negatively charged.
D
Because histones are enzymes that catalyze DNA replication.
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1
Understand the structure of DNA: DNA is composed of nucleotides, each containing a phosphate group, which gives DNA a negative charge.
Learn about histones: Histones are proteins that help package DNA into structural units called nucleosomes. They are rich in basic amino acids like lysine and arginine.
Recognize the charge properties: Basic amino acids in histones carry a positive charge due to their side chains.
Apply the concept of charge attraction: Opposite charges attract, so the positively charged histones bind tightly to the negatively charged DNA.
Conclude the reason for binding: The electrostatic attraction between the positive charges on histones and the negative charges on DNA is the primary reason for their tight binding.