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What do Alzheimer's, Parkinson's, and mad cow disease have in common?
A
All cause the misfolding of nucleic acids.
B
All are associated with plaque buildup in arteries (atherosclerosis).
C
All are caused by the buildup of misfolded proteins in cells.
D
All are associated with the buildup of lipids in brain cells due to faulty lysosome activity.
E
All are associated with the buildup of misfolded proteins in cells.
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1
Understand the nature of the diseases mentioned: Alzheimer's, Parkinson's, and mad cow disease are all neurodegenerative diseases.
Recognize that these diseases are linked to protein misfolding: In these conditions, proteins do not fold into their normal configurations, leading to dysfunction.
Identify the role of misfolded proteins: Misfolded proteins can aggregate and form plaques or fibrils, which are toxic to cells.
Eliminate incorrect options: These diseases are not primarily caused by nucleic acid misfolding, atherosclerosis, or lipid buildup due to lysosome activity.
Conclude that the commonality among these diseases is the buildup of misfolded proteins in cells, which disrupts normal cellular function.