exam 3
Termini in questo insieme (56)
allelle
form of a gene
character
trait
trait
option
codominance
both genes are dominant
ex. brown and white spots
complete dominance
one gene is dominant over the other
incomplete dominance
two of the gene has to be present for it to show up
if both are present, it results in a unique phenotype
ex. pink flowers
F1 generation
daughter
F2 generation
grandaughters
hungtingtons disease
autosomal disease on chromosome 4
hybrid
a mix between two genetically different organism
law of segregation
alleles separate during gamete formation, only one allele is passed down to child
pleitropy
one gener or mutation that affects multiple phenotypic traits ex. sickle cell anemia
polygenic inheritance
one trait controlled by multiple genes ex. heigh, weight
sickle cell
autosomal disease that affects your blood cells. it stiffens then and makes them a crest like shape.
true breeding
always produces the same phenotypic traits
wildtype
"normal"
polygenic
multiple genes affects one trait
bacteriophage
virus that affects bacteria
Structure of DNA
Double helix, anti parallel- 5' 3', 3' 5'
Composed of nucleotide
- 5 carbon sugar
Phosphorus group - Po4-
Nitrogenous base - ATCG
A goes to?
T
G goes to?
C
Pyramadines
Thyanine, Cytosine
Purine
Guanine
Adenine
RNA structure
Single stranded
Uracil
Nucelotide
Sugar with hydroxyl group attached
codon
3 sequences nucleotide on mRNA that codes for specific proteins
anticodon
complementary sequence on tRNA that binds to the codon
DNA liagase
Links okazaki fragments
DNA polymerase
Adds DNA nucleotides
Involved in proof reading
exon
coding regions expressed as proteins in mRNA
intron
intruding sequence that gets spliced out
framshift mutation
a mutation caused by the deletion of the nucleotides bases
missense mutation
change in the dna that causes it to code for the wrong protein
nonsense mutation
change in the dna that causes a premature stop
silent mutation
change in DNA that does not affect anything
ribosome
protein synthesis
RNA splicing
cuts out introns, keeps exons
semiconservative model
DNA will keep one parent strand and produce a new daughter strand
Start codon
AUG
Stop codon
3 Types
Tells it to stop protein synthesis
What happens during transcription
DNA is turned into RNA
Three steps and explanation
Initiation - RNA polymerase binds and attaches to promoter region
Elongation - RNA polymerase copies to elongate strand
Termination - RNA detaches from DNA
trna
acts as an adaptor between mrna and amino acids
What happens during trasnlation
RNA synthesizes to a protein
Three steps of translation
Initiation - mrna bonds to small subunit and finds the start codon. trna brings methyanine
elongation - mrna binds to large subunit, trna brings apropriate amino acid
termination - stop codon is reached, protein is released, mrna is released
alternative rna splicing
exon from single transcribed gene are joined in different combinations
Barr body
inactivated x chromosome
carcinogen
harmful things:
radiation, cigarettes, etc
causes cancer
DNA microarray
uses fluorescent lights to help find expressed traits
red = expressed in diseased
green = expressed in normal
yellow = expressed in none
epigenetic inheritance
methyl tags added onto histone proteins that are passed down
histone
protein that packages dna
nucelosome
structura unit of DNA
microRNA
destructs or silences RNA - regulated gene expression
oncogene
mutated gene/ tumor
proto-oncogene
normal gene that promotes cell division
tumor supressor gene
gene that stops cell division
sirna
degrades one specific mrna (not natural)