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Indietro

exam 3

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  • allelle


    form of a gene

  • character


    trait

  • trait


    option

  • codominance


    both genes are dominant

    ex. brown and white spots

  • complete dominance


    one gene is dominant over the other

  • incomplete dominance


    two of the gene has to be present for it to show up

    if both are present, it results in a unique phenotype

    ex. pink flowers

  • F1 generation


    daughter

  • F2 generation


    grandaughters

  • hungtingtons disease


    autosomal disease on chromosome 4

  • hybrid


    a mix between two genetically different organism

  • law of segregation


    alleles separate during gamete formation, only one allele is passed down to child

  • pleitropy


    one gener or mutation that affects multiple phenotypic traits ex. sickle cell anemia

  • polygenic inheritance


    one trait controlled by multiple genes ex. heigh, weight

  • sickle cell


    autosomal disease that affects your blood cells. it stiffens then and makes them a crest like shape.

  • true breeding


    always produces the same phenotypic traits

  • wildtype


    "normal"

  • polygenic


    multiple genes affects one trait

  • bacteriophage


    virus that affects bacteria

  • Structure of DNA


    Double helix, anti parallel- 5' 3', 3' 5'

    Composed of nucleotide

    • - 5 carbon sugar

    • Phosphorus group - Po4-

    • Nitrogenous base - ATCG

  • A goes to?


    T

  • G goes to?


    C

  • Pyramadines


    Thyanine, Cytosine

  • Purine


    Guanine

    Adenine

  • RNA structure


    Single stranded

    Uracil

    Nucelotide

    • Sugar with hydroxyl group attached

  • codon


    3 sequences nucleotide on mRNA that codes for specific proteins

  • anticodon


    complementary sequence on tRNA that binds to the codon

  • DNA liagase


    Links okazaki fragments

  • DNA polymerase


    Adds DNA nucleotides

    Involved in proof reading

  • exon


    coding regions expressed as proteins in mRNA

  • intron


    intruding sequence that gets spliced out

  • framshift mutation


    a mutation caused by the deletion of the nucleotides bases

  • missense mutation


    change in the dna that causes it to code for the wrong protein

  • nonsense mutation


    change in the dna that causes a premature stop

  • silent mutation


    change in DNA that does not affect anything

  • ribosome


    protein synthesis

  • RNA splicing


    cuts out introns, keeps exons

  • semiconservative model


    DNA will keep one parent strand and produce a new daughter strand

  • Start codon


    AUG

  • Stop codon


    3 Types

    • Tells it to stop protein synthesis

  • What happens during transcription


    DNA is turned into RNA

  • Three steps and explanation


    1. Initiation - RNA polymerase binds and attaches to promoter region

    2. Elongation - RNA polymerase copies to elongate strand

    3. Termination - RNA detaches from DNA

  • trna


    acts as an adaptor between mrna and amino acids

  • What happens during trasnlation


    RNA synthesizes to a protein

  • Three steps of translation


    1. Initiation - mrna bonds to small subunit and finds the start codon. trna brings methyanine

    2. elongation - mrna binds to large subunit, trna brings apropriate amino acid

    3. termination - stop codon is reached, protein is released, mrna is released

  • alternative rna splicing


    exon from single transcribed gene are joined in different combinations

  • Barr body


    inactivated x chromosome

  • carcinogen


    harmful things:

    radiation, cigarettes, etc

    • causes cancer

  • DNA microarray


    uses fluorescent lights to help find expressed traits

    red = expressed in diseased

    green = expressed in normal

    yellow = expressed in none

  • epigenetic inheritance


    methyl tags added onto histone proteins that are passed down

  • histone


    protein that packages dna

  • nucelosome


    structura unit of DNA

  • microRNA


    destructs or silences RNA - regulated gene expression

  • oncogene


    mutated gene/ tumor

  • proto-oncogene


    normal gene that promotes cell division

  • tumor supressor gene


    gene that stops cell division

  • sirna


    degrades one specific mrna (not natural)