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Ch. 43 - The Immune System
Campbell - Campbell Biology 12th Edition
Urry12th EditionCampbell BiologyISBN: 9785794169850Non è quello che usi tu?Cambia libro di testo
Tutti i libri di testoUrry 12th EditionCh. 43 - The Immune SystemProblema 5
Capitolo 43, Problema 5

Which of the following should be the same in identical twins?
a. The set of antibodies produced
b. The set of MHC molecules produced
c. The set of T cell antigen receptors produced
d. The set of immune cells eliminated as self-reactive

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1
Understand that identical twins originate from the same fertilized egg, meaning they have the same genetic material.
Recall that the Major Histocompatibility Complex (MHC) molecules are encoded by genes that are highly polymorphic, but identical twins have the same alleles for these genes.
Consider that the set of antibodies produced can vary due to environmental factors and exposure to different pathogens, even in identical twins.
Recognize that T cell antigen receptors are generated through a random recombination process, which can lead to differences even in genetically identical individuals.
Identify that the set of immune cells eliminated as self-reactive is influenced by the genetic makeup, which is identical in twins, leading to the same set of self-reactive cells being eliminated.

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Identical Twins

Identical twins, also known as monozygotic twins, originate from a single fertilized egg that splits into two embryos. This results in twins with identical genetic material, meaning they share the same DNA. This genetic similarity is crucial for understanding why certain biological characteristics, such as genetic markers, are the same in identical twins.
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Homologous Chromosomes

Major Histocompatibility Complex (MHC)

The Major Histocompatibility Complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules. MHC molecules are encoded by a highly polymorphic set of genes, meaning they vary greatly between individuals. However, identical twins have the same set of MHC molecules due to their identical genetic makeup, which is critical for tissue compatibility and immune response.
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Major Histocompatibility Complex

T Cell Antigen Receptors

T cell antigen receptors are molecules found on the surface of T cells that allow them to recognize and bind to specific antigens. These receptors are generated through a process of genetic recombination, leading to a diverse repertoire in each individual. In identical twins, the genetic potential for producing T cell receptors is the same, but the actual set of receptors can differ due to random recombination events during immune cell development.
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Antigen Receptors
Pratica correlata
Domanda del libro di testo

An epitope associates with which part of an antigen receptor or antibody?

a. The tail

b. The heavy-chain constant regions only

c. Variable regions of a heavy chain and light chain combined

d. The light-chain constant regions only

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Domanda del libro di testo

Which statement best describes the difference between responses of effector B cells (plasma cells) and those of cytotoxic T cells?

a. B cells confer active immunity; cytotoxic T cells confer passive immunity.

b. B cells respond the first time a pathogen is present; cytotoxic T cells respond subsequent times.

c. B cells secrete antibodies against a pathogen; cytotoxic T cells kill pathogen-infected host cells.

d. B cells carry out the cell-mediated response; cytotoxic T cells carry out the humoral response.

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Domanda del libro di testo

Which of the following statements is true?

a. An antibody has one antigen-binding site

b. A lymphocyte has receptors for a single antigen

c. Every antigen has a single epitope

d. A liver or muscle cell makes two classes of MHC molecule

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