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Ch. 18 - Control of Gene Expression in Bacteria
Freeman - Biological Science 8th Edition
Freeman8th EditionBiological ScienceISBN: 9780138276263Non è quello che usi tu?Cambia libro di testo
Capitolo 18, Problema 3

Activators bind to regulatory sequences in ________ and to ________ polymerase.

Guida verificata passo dopo passo
1
Step 1: Understand the question. The question is asking for two missing terms related to the function of activators in gene expression.
Step 2: Recall that activators are proteins that increase the transcription of a gene. They do this by binding to specific DNA sequences and to other proteins.
Step 3: Identify the first missing term. Activators bind to regulatory sequences in the DNA. These sequences are often located in the promoter region of a gene, but can also be found in enhancers or other regulatory regions.
Step 4: Identify the second missing term. Activators also bind to other proteins involved in transcription. The main protein they bind to is RNA polymerase, the enzyme that synthesizes RNA from a DNA template.
Step 5: Fill in the blanks with the correct terms. Activators bind to regulatory sequences in DNA and to RNA polymerase.

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Regulatory Sequences

Regulatory sequences are specific regions of DNA that control the expression of genes. They include promoters, enhancers, and silencers, which interact with transcription factors and other proteins to regulate when and how much a gene is expressed. Understanding these sequences is crucial for grasping how gene expression is modulated in response to various signals.
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Dideoxy Sequencing

Transcription Factors

Transcription factors are proteins that bind to specific DNA sequences, influencing the transcription of genes. They can act as activators or repressors, either promoting or inhibiting the recruitment of RNA polymerase to the gene's promoter. Their role is essential in the regulation of gene expression, allowing cells to respond to internal and external stimuli.
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Introduction to Transcription Factors

RNA Polymerase

RNA polymerase is the enzyme responsible for synthesizing RNA from a DNA template during the process of transcription. It binds to the promoter region of a gene, where it initiates the transcription process. Understanding the function of RNA polymerase is vital for comprehending how genetic information is converted into functional products, such as proteins.
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DNA Polymerase Requirements
Pratica correlata
Domanda del libro di testo

Why are the genes involved in lactose metabolism considered to be an operon?

a. They occupy adjacent locations on the E. coli chromosome.

b. They have a similar function.

c. They are all required for normal cell function.

d. They are all controlled by the same promoter.

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A regulon is a set of genes controlled by

a. One type of regulator of transcription

b. Two or more different alternative sigma proteins

c. Many different types of promoters

d. Glucose

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In the lac operon, the repressor inhibits transcription when

a. The repressor is bound to the inducer.

b. The repressor is not bound to the inducer.

c. The repressor is bound to glucose.

d. The repressor is not bound to the operator.

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Evaluate these statements about regulation of the lac operon. Select True or False for each statement.

T/FThe lac operon is transcribed at the highest rate when extracellular glucose and lactose are abundant.

T/FThe repressor protein is bound to DNA of the operator when lactose is present.

T/FA mutation in the operator is likely to prevent transcription of the lac operon under any condition.

T/FA mutation that alters the catabolite activator protein is predicted to alter the regulation of many different operons.

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Predict what would happen to regulation of the lac operon if the lacI gene were moved 50,000 nucleotides upstream of its normal location.

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