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During which phase of mitosis do chromosomes first condense and become visibly distinct under a light microscope?
A
Metaphase
B
Telophase
C
Anaphase
D
Prophase
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1
Recall the stages of mitosis: prophase, metaphase, anaphase, and telophase, each with distinct cellular events.
Understand that chromosome condensation is the process where chromatin fibers become tightly coiled, making chromosomes visible under a light microscope.
Identify that chromosome condensation and the appearance of distinct chromosomes occur at the beginning of mitosis.
Recognize that this event specifically happens during prophase, the first phase of mitosis.
Confirm that in metaphase, chromosomes are aligned at the cell equator; in anaphase, sister chromatids separate; and in telophase, chromosomes decondense, so these phases occur after chromosome condensation.