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During mitosis in animal cells, which organelle serves as the microtubule-organizing center that anchors the spindle fibers at each pole?
A
Nucleolus
B
Centrosome (containing a pair of centrioles)
C
Golgi apparatus
D
Rough endoplasmic reticulum
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1
Understand the role of the microtubule-organizing center (MTOC) during mitosis: it is responsible for nucleating and anchoring microtubules that form the spindle fibers.
Recall that in animal cells, the organelle that acts as the MTOC is the centrosome, which contains a pair of centrioles.
Recognize that the centrosomes move to opposite poles of the cell during mitosis to help organize the spindle apparatus.
Note that other organelles listed, such as the nucleolus, Golgi apparatus, and rough endoplasmic reticulum, do not function as MTOCs or anchor spindle fibers.
Conclude that the centrosome (with centrioles) is the correct organelle serving as the microtubule-organizing center anchoring spindle fibers at each pole during mitosis.