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What is the starting molecule for the citric acid cycle?
A
Glucose
B
Pyruvate
C
Acetyl CoA
D
Citrate
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1
Understand that the citric acid cycle, also known as the Krebs cycle, is a key metabolic pathway that takes place in the mitochondria of cells.
Recognize that the citric acid cycle begins with the combination of Acetyl CoA and oxaloacetate to form citrate.
Recall that glucose is initially broken down through glycolysis into pyruvate in the cytoplasm.
Know that pyruvate is then transported into the mitochondria where it is converted into Acetyl CoA by the enzyme pyruvate dehydrogenase.
Identify Acetyl CoA as the starting molecule that enters the citric acid cycle by combining with oxaloacetate to form citrate, which is the first step of the cycle.