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In eukaryotic cells, in which part of the cell does glycolysis primarily take place?
A
Rough endoplasmic reticulum
B
Cytosol (cytoplasm)
C
Nucleus
D
Mitochondrial matrix
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1
Recall that glycolysis is the metabolic pathway that breaks down glucose into pyruvate, producing ATP and NADH in the process.
Understand that glycolysis occurs in the part of the cell where enzymes for this pathway are freely available and not enclosed within membrane-bound organelles.
Identify that the cytosol (also called cytoplasm) is the fluid portion of the cell outside organelles where many metabolic reactions take place.
Recognize that the rough endoplasmic reticulum is primarily involved in protein synthesis, the nucleus contains genetic material, and the mitochondrial matrix is the site of the Krebs cycle and oxidative phosphorylation, not glycolysis.
Conclude that glycolysis primarily takes place in the cytosol (cytoplasm) of eukaryotic cells.