design-an-experiment-to-test-the-effect-of-a-novel-ligand-on-the-activation-of-a

Question

Design an experiment to test the effect of a novel ligand on the activation of a receptor tyrosine kinase. What would be a key indicator of receptor activation?

Accepted Answer

Increased phosphorylation of the receptor.

Answer

Increased receptor degradation.

Answer

Decreased ligand binding affinity.

Answer

Decreased receptor dimerization.