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Tumor Viruses definitions

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Termini in questo insieme (15)

  • Oncogenic Viruses
    Agents capable of initiating cancer by altering host cell genetic material or producing proteins that disrupt normal cellular regulation.
  • Viral Genome Integration
    Process where foreign genetic material becomes part of host DNA, potentially disrupting key genes and promoting malignancy.
  • RAS
    A GTPase frequently mutated in cancers, whose function can be compromised by insertion of foreign genetic material.
  • Tumor Suppressor
    Cellular component that prevents uncontrolled growth; its inhibition or destruction increases cancer risk.
  • Cell Cycle Control
    Regulatory system ensuring orderly cell division; disruption can favor unchecked proliferation.
  • Apoptosis
    Programmed cell death mechanism; its reduction allows abnormal cells to survive and multiply.
  • DNA Replication
    Cellular process hijacked by viruses to duplicate their own genetic material within host cells.
  • Hepatitis B
    Virus linked to liver cancer, known for its ability to alter host cell functions and promote malignancy.
  • Hepatitis C
    Pathogen associated with liver cancer, contributing to oncogenesis through chronic infection.
  • Human Papillomavirus
    Virus implicated in cervical, head, neck, and throat cancers, expressing proteins that disrupt tumor suppression.
  • E6
    Protein that binds and leads to the destruction of a key tumor suppressor, facilitating cancer development.
  • E7
    Protein that inhibits the function of the retinoblastoma tumor suppressor, increasing cancer susceptibility.
  • Retinoblastoma Tumor Suppressor
    Cellular regulator of proliferation, whose inhibition by viral proteins raises the likelihood of tumor formation.
  • Kaposi Sarcoma
    Cancer often seen in immunocompromised individuals, associated with herpes virus infection.
  • AIDS
    Immunodeficiency condition that increases vulnerability to oncogenic viral infections and related cancers.