Scelta multipla
Consider an organism with a diploid chromosome number of 2n = 20. Which of the following represents an example of aneuploidy in this organism?
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6. Chromosomal Variation
Chromosomal Mutations: Aneuploidy
Scelta multipla
If nondisjunction occurs during meiosis and an individual survives, which of the following chromosomal conditions is most likely to be observed?
A
Polyploidy, with entire extra sets of chromosomes
B
No change in chromosome number
C
Deletion of a single gene
D
Aneuploidy, such as trisomy or monosomy
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Understand the concept of nondisjunction: it is the failure of homologous chromosomes or sister chromatids to separate properly during meiosis I or meiosis II, respectively.
Recognize that nondisjunction leads to gametes with abnormal numbers of chromosomes, either extra or missing chromosomes, rather than entire extra sets of chromosomes.
Recall that polyploidy refers to having entire extra sets of chromosomes (e.g., triploidy), which usually results from errors in cell division other than nondisjunction during meiosis.
Identify that deletion of a single gene is a small-scale mutation and not related to nondisjunction, which affects whole chromosomes.
Conclude that the chromosomal condition most likely observed after nondisjunction is aneuploidy, which includes trisomy (an extra chromosome) or monosomy (a missing chromosome).
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