Scelta multipla
Which DNA repair process specifically corrects damage to a preexisting double helix, such as mismatched bases or distortions in the DNA structure?
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17. Mutation, Repair, and Recombination
DNA Repair
Scelta multipla
Short segments of newly synthesized DNA are joined into a continuous strand by _____.
A
DNA ligase
B
Topoisomerase
C
Helicase
D
DNA polymerase
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Understand the process of DNA replication, where the double helix is unwound and new strands are synthesized.
Recognize that the lagging strand is synthesized in short fragments called Okazaki fragments.
Identify that these Okazaki fragments need to be joined together to form a continuous strand.
Recall the enzyme responsible for joining these short DNA segments is DNA ligase, which catalyzes the formation of phosphodiester bonds between fragments.
Differentiate DNA ligase from other enzymes like topoisomerase (which relieves supercoiling), helicase (which unwinds DNA), and DNA polymerase (which synthesizes new DNA strands).
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