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In cats, the calico fur pattern is due to X-linked genes. Which meiotic error could produce a gamete that, when fertilized, results in a calico male (an XXY individual)?
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2. Mendel's Laws of Inheritance
Sex-Linked Genes
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In a sex-linked pedigree, if females are labeled as 'XX', how should males be labeled?
A
XXY
B
XY
C
YY
D
XYY
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Understand that in humans, sex determination is based on the combination of sex chromosomes: females have two X chromosomes, labeled as 'XX'.
Recognize that males have one X chromosome and one Y chromosome, which is why they are labeled as 'XY'.
Note that 'XXY' and 'XYY' represent abnormal or atypical chromosomal patterns (such as Klinefelter syndrome and XYY syndrome), not the typical male genotype.
Understand that 'YY' is not a viable chromosomal combination for humans because the X chromosome carries essential genes necessary for survival.
Therefore, in a sex-linked pedigree, males should be labeled as 'XY' to represent the typical male chromosomal pattern.
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