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Which components form the sides (backbone) of the DNA ladder?
A
Ribose sugars and uracil bases
B
Alternating deoxyribose sugars and phosphate groups
C
Nitrogenous bases paired together
D
Amino acids linked by peptide bonds
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1
Recall the structure of DNA, which is often described as a double helix resembling a twisted ladder.
Identify the components of the DNA ladder: the 'sides' or backbone and the 'rungs' or steps.
Understand that the backbone of DNA is made up of alternating sugar and phosphate groups linked together by covalent bonds.
Recognize that in DNA, the sugar is deoxyribose, not ribose (which is found in RNA), and that the phosphate groups connect these sugars.
Note that the nitrogenous bases (adenine, thymine, cytosine, guanine) form the rungs of the ladder by pairing together through hydrogen bonds, not the backbone.