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In the DNA double helix, what are the “rungs” of the DNA ladder made of?
A
Pairs of ribose sugars connected by hydrogen bonds
B
Paired nitrogenous bases (A with T, and G with C) held together by hydrogen bonds
C
Alternating deoxyribose sugars and phosphate groups linked by phosphodiester bonds
D
Stacks of amino acids joined by peptide bonds
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1
Recall the structure of the DNA double helix, which resembles a twisted ladder.
Identify the components of the DNA ladder: the sides (or backbone) and the rungs (the steps between the sides).
Understand that the backbone is made of alternating deoxyribose sugars and phosphate groups linked by phosphodiester bonds.
Recognize that the rungs of the ladder are formed by pairs of nitrogenous bases (adenine pairs with thymine, and guanine pairs with cytosine) held together by hydrogen bonds.
Conclude that the "rungs" specifically refer to these paired nitrogenous bases connected by hydrogen bonds, not sugars, phosphates, or amino acids.