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Which of the following is an exception to the one gene–one enzyme hypothesis?
A
A gene encoding a single enzyme that catalyzes one reaction
B
A gene that is inherited independently of other genes
C
A single gene encoding multiple polypeptides through alternative splicing
D
A gene that is not transcribed into mRNA
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1
Understand the one gene–one enzyme hypothesis, which states that each gene encodes a single enzyme that catalyzes a specific reaction.
Review each option to see if it fits or contradicts this hypothesis:
Option 1 describes a gene encoding a single enzyme catalyzing one reaction, which aligns with the hypothesis.
Option 2 refers to gene inheritance patterns, which is unrelated to the one gene–one enzyme concept.
Option 3 mentions a single gene encoding multiple polypeptides through alternative splicing, which is an exception because one gene can produce multiple protein products, not just one enzyme.
Option 4 describes a gene not transcribed into mRNA, which does not directly contradict the hypothesis but relates to gene expression.