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Transcription in Prokaryotes definitions
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Promoter
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Promoter
A DNA sequence upstream of a gene that recruits proteins to initiate RNA synthesis in prokaryotes.
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Termini in questo insieme (15)
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Promoter
A DNA sequence upstream of a gene that recruits proteins to initiate RNA synthesis in prokaryotes.
Consensus Sequence
A DNA region with similar, but not identical, nucleotide patterns found across prokaryotic species, guiding transcription initiation.
Pribnow Box
A common promoter element located 10 base pairs upstream of the transcription start site, crucial for RNA polymerase binding.
RNA Polymerase Holoenzyme
A multi-component enzyme complex responsible for catalyzing RNA synthesis, including both core and specificity factors.
Core Enzyme
The catalytic portion of RNA polymerase that synthesizes RNA but lacks specificity for promoter recognition.
Sigma Factor
A detachable protein subunit that directs RNA polymerase to specific promoter sequences, determining which RNA is transcribed.
Transcription Bubble
A locally unwound DNA region, about 18 nucleotides long, where active RNA synthesis occurs during elongation.
Termination Sequence
A DNA region signaling the end of transcription, leading to release of the RNA transcript and dissociation of the polymerase.
Rho-dependent Termination
A process where a specific protein factor binds RNA, facilitating transcript release at the end of a gene.
Rho-independent Termination
A mechanism where RNA forms a structure that causes polymerase to detach without the need for additional proteins.
Intrinsic Termination
A rare process where weak uracil-rich RNA-DNA bonds cause spontaneous dissociation of the transcript.
Polycistronic mRNA
A single RNA molecule containing multiple gene sequences, allowing coordinated expression of several proteins.
Transcription Initiation
The stage where RNA polymerase and associated factors assemble at the promoter to begin RNA synthesis.
Transcription Elongation
The phase where RNA polymerase moves along DNA, synthesizing RNA within the transcription bubble.
Transcription Termination
The final stage of transcription, involving release of the RNA transcript and dissociation of the polymerase from DNA.