Question

Experiments have shown that any nuclei placed in the polar cytoplasm at the posterior pole of the Drosophila egg will differentiate into germ cells. If polar cytoplasm is transplanted into the anterior end of the egg just after fertilization, what will happen to nuclei that migrate into this cytoplasm at the anterior pole?

Accepted Answer

Understand the concept of polar cytoplasm: In Drosophila development, the polar cytoplasm at the posterior pole contains determinants that specify germ cell fate. These determinants are critical for the differentiation of nuclei into germ cells. Recognize the experimental setup: The problem describes a scenario where polar cytoplasm is transplanted from the posterior pole to the anterior pole of the egg after fertilization. This means the anterior pole now contains the same germ cell determinants as the posterior pole. Consider the behavior of nuclei: Nuclei that migrate into the polar cytoplasm at the posterior pole normally differentiate into germ cells due to the presence of germ cell determinants. Similarly, nuclei that migrate into the transplanted polar cytoplasm at the anterior pole will encounter the same determinants. Predict the outcome: Since the anterior pole now contains polar cytoplasm with germ cell determinants, any nuclei that migrate into this region will likely differentiate into germ cells, just as they would at the posterior pole. Conclude the reasoning: The transplantation of polar cytoplasm effectively creates a second region in the egg where germ cell differentiation can occur, leading to the formation of germ cells at both the anterior and posterior poles.

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Concetti chiave

Polar Cytoplasm

Germ Cell Differentiation

Nuclear Migration