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07:33In assessing data that fell into two phenotypic classes, a geneticist observed values of 250:150. She decided to perform a ² analysis by using the following two different null hypotheses:
(a) the data fit a 3:1 ratio, and
(b) the data fit a 1:1 ratio.
Calculate the ² values for each hypothesis. What can be concluded about each hypothesis?
Thalassemia is an inherited anemic disorder in humans. Affected individuals exhibit either a minor anemia or a major anemia. Assuming that only a single gene pair and two alleles are involved in the inheritance of these conditions, is thalassemia a dominant or recessive disorder?
Mendel crossed peas having round green seeds with peas having wrinkled yellow seeds. All F₁ plants had seeds that were round and yellow. Predict the results of testcrossing these F₁ plants.
In a study of black guinea pigs and white guinea pigs, 100 black animals were crossed with 100 white animals, and each cross was carried to an F₂ generation. In 94 of the crosses, all the F₁ offspring were black and an F₂ ratio of 3 black:1 white was obtained. In the other 6 cases, half of the F₁ animals were black and the other half were white. Why? Predict the results of crossing the black and white F₁ guinea pigs from the 6 exceptional cases.
The basis for rejecting any null hypothesis is arbitrary. The researcher can set more or less stringent standards by deciding to raise or lower the p value used to reject or not reject the hypothesis. In the case of the chi-square analysis of genetic crosses, would the use of a standard of p = 0.10 be more or less stringent about not rejecting the null hypothesis? Explain.
Consider the following pedigree.
Predict the mode of inheritance of the trait of interest and the most probable genotype of each individual. Assume that the alleles A and a control the expression.
