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Microbiology Chapter 1: The Microbial World

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  • What are microorganisms?

    Microorganisms are living things too small to be seen with the unaided eye and are found everywhere, including on and in the human body.

  • Name three helpful roles of microorganisms.

    They decompose dead plants and animals, recycle chemical elements, and help maintain human health as normal microbiota.

  • What is binomial nomenclature?

    A system of naming organisms using two names: the genus (capitalized) and the specific epithet (lowercase), both italicized or underlined.

  • Key characteristics of bacteria

    Bacteria are unicellular, prokaryotic, usually have peptidoglycan cell walls, reproduce by binary fission, and may have flagella.

  • How do archaea differ from bacteria?

    Archaea are prokaryotic but lack peptidoglycan in their cell walls and often live in extreme environments.

  • What distinguishes fungi from other microorganisms?

    Fungi are eukaryotic, mostly multicellular, have a true nucleus, and obtain nutrients by absorbing organic material.

  • What are protozoa?

    Unicellular eukaryotes that obtain nutrients by absorption or ingestion through specialized structures.

  • How do algae obtain nutrients?

    Algae are eukaryotic and obtain nourishment through photosynthesis, producing oxygen and carbohydrates.

  • Basic structure of viruses

    Viruses are noncellular entities with a nucleic acid core (DNA or RNA), a protein coat called a capsid, and sometimes an outer envelope.

  • What are helminths?

    Multicellular parasitic worms including flatworms and roundworms.

  • What are the three domains of life?

    Bacteria (prokaryotic), Archaea (prokaryotic without peptidoglycan), and Eukarya (eukaryotic with nucleus).

  • Who first observed cells and contributed to cell theory?

    Robert Hooke observed cork cells and helped establish the foundation for cell theory.

  • Who was the first to observe microorganisms?

    Antonie van Leeuwenhoek, using a simple microscope around 1673.

  • What is spontaneous generation?

    The disproven belief that living organisms can arise from nonliving matter.

  • What did Francesco Redi demonstrate in 1668?

    Maggots on decaying meat come from flies laying eggs, not spontaneous generation.

  • What was John Needham's contribution to spontaneous generation debate?

    He heated nutrient broth and observed microbial growth, interpreting it as support for spontaneous generation.

  • How did Lazzaro Spallanzani challenge Needham's results?

    He heated broth more thoroughly and sealed containers, preventing microbial growth and suggesting contamination caused Needham's results.

  • Define biogenesis.

    The concept that living cells arise only from preexisting cells, introduced by Rudolf Virchow in 1858.

  • What was Louis Pasteur's swan-neck flask experiment conclusion?

    Microorganisms come from existing microorganisms, disproving spontaneous generation.

  • What is pasteurization?

    A heating process to kill or reduce harmful microorganisms in products like milk, without sterilizing them.

  • What are Koch's postulates?

    Four steps to prove a specific microorganism causes a specific disease: presence, isolation, causation, and re-isolation.

  • Who developed the first vaccine and against which disease?

    Edward Jenner used cowpox material to provide immunity against smallpox in 1798.

  • What is an avirulent organism?

    An organism with little or no ability to cause disease, used in some vaccines.

  • Difference between synthetic drugs and antibiotics

    Synthetic drugs are chemically made in labs; antibiotics are naturally produced by bacteria or fungi to inhibit bacterial growth.

  • What did Alexander Fleming discover in 1928?

    Penicillin, an antibiotic produced by the Penicillium fungus that inhibits bacterial growth.

  • What is biotechnology in microbiology?

    The use of microorganisms to produce foods, chemicals, proteins, enzymes, and vaccines.

  • How is gene therapy related to microbiology?

    Viruses can be used to deliver genes into human cells to replace or compensate for defective genes.

  • What is a biofilm?

    A community of microorganisms forming a slimy layer on surfaces, protecting microbes from antimicrobials and host defenses.

  • Define infectious disease.

    A disease caused when pathogens invade a susceptible host.

  • What factors contribute to emerging infectious diseases?

    Changes in microorganisms, genetics, human behavior, environment, travel, and drug resistance.