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Microbiology Fundamentals: Key Concepts and Terms

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  • Abiogenesis

    Abiogenesis is the hypothesis that life arose naturally from non-living matter on early Earth.

  • Antiseptic Technique

    Antiseptic technique involves practices used to prevent contamination by pathogens during medical procedures.

  • Germ Theory of Disease

    The germ theory of disease states that microorganisms are the cause of many diseases.

  • Koch's Postulates

    Koch's postulates are criteria used to establish a causative relationship between a microbe and a disease.

  • Microorganisms

    Microorganisms are microscopic organisms including bacteria, fungi, protozoa, and viruses.

  • Pathogen / Pathogenic

    A pathogen is a microorganism that causes disease; pathogenic describes its disease-causing ability.

  • Prontosil (Sulfa Drugs)

    Prontosil was the first sulfa drug used as chemotherapy to treat bacterial infections.

  • Scientific Method

    The scientific method is a systematic process of observation, hypothesis, experimentation, and conclusion.

  • Spontaneous Generation

    Spontaneous generation is the disproven idea that living organisms arise from nonliving matter spontaneously.

  • Taxonomic System

    The taxonomic system classifies organisms into hierarchical groups based on shared characteristics.

  • Viruses / Virology

    Viruses are acellular infectious agents studied in virology that require host cells to replicate.

  • ATP

    ATP (adenosine triphosphate) is the primary energy carrier molecule in cells.

  • Anabolism

    Anabolism is the metabolic process of building complex molecules from simpler ones, requiring energy.

  • Catabolism

    Catabolism is the metabolic breakdown of complex molecules into simpler ones, releasing energy.

  • Chemical Bonds

    Chemical bonds are forces holding atoms together, including covalent, ionic, and hydrogen bonds.

  • Covalent Bond

    A covalent bond forms when atoms share electron pairs to achieve stability.

  • Hydrogen Bond

    A hydrogen bond is a weak attraction between a hydrogen atom and an electronegative atom.

  • pH

    pH measures the acidity or alkalinity of a solution on a scale from 0 to 14.

  • Polysaccharide

    Polysaccharides are large carbohydrate polymers made of many monosaccharide units.

  • Protein Primary Structure

    The primary structure of a protein is its unique sequence of amino acids linked by peptide bonds.

  • Denaturation

    Denaturation is the loss of a protein's native structure due to external stress, affecting function.

  • Nucleic Acids

    Nucleic acids like DNA and RNA store and transmit genetic information.

  • Peptide Bond

    A peptide bond is a covalent bond linking amino acids in a protein chain.

  • Buffers

    Buffers maintain stable pH by neutralizing added acids or bases in biological systems.

  • Electronegativity

    Electronegativity is an atom's ability to attract electrons in a chemical bond.

  • Monosaccharide

    A monosaccharide is the simplest carbohydrate unit, such as glucose or fructose.

  • Hydrophilic vs Hydrophobic

    Hydrophilic molecules interact with water; hydrophobic molecules repel water.

  • Dehydration Synthesis

    Dehydration synthesis joins monomers by removing water to form polymers.

  • Hydrolysis

    Hydrolysis breaks polymers into monomers by adding water.