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Ch. 18 - Nervous System Infections
Norman-McKay- Microbiology: Basic and Clinical Principles 2nd Edition
Norman-McKay2nd EditionMicrobiology: Basic and Clinical PrinciplesISBN: 9780137661619Non è quello che usi tu?Cambia libro di testo
Capitolo 14, Problema 2

Viral meningitis is more common than other forms of meningitis because
a. these infectious agents are all intracellular, evading the immune system.
b. there are more types of viruses than bacteria because they evolve more quickly.
c. the small size of viruses makes them able to pass more easily through the blood–brain barrier.
d. viruses are spread person to person more easily than bacteria, fungi, or protozoans.

Guida verificata passo dopo passo
1
Step 1: Understand the context of viral meningitis and why it is more common compared to other forms of meningitis caused by bacteria, fungi, or protozoans.
Step 2: Analyze option (a): Consider whether the intracellular nature of viruses helps them evade the immune system and if this contributes to their higher incidence in meningitis cases.
Step 3: Analyze option (b): Reflect on the diversity and rapid evolution of viruses compared to bacteria, and how this might affect the frequency of viral meningitis.
Step 4: Analyze option (c): Evaluate if the small size of viruses allows them to cross the blood–brain barrier more easily than other pathogens, leading to more cases of viral meningitis.
Step 5: Analyze option (d): Consider the modes of transmission of viruses compared to bacteria, fungi, and protozoans, and whether easier person-to-person spread explains the higher prevalence of viral meningitis.

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Blood–Brain Barrier and Pathogen Entry

The blood–brain barrier is a selective barrier that protects the brain from pathogens and toxins. Its structure limits the passage of many microorganisms, but some viruses can cross it due to their small size or specific mechanisms, influencing the incidence of viral meningitis.
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Introduction to Pathogenic Toxins

Viral Evolution and Diversity

Viruses evolve rapidly due to high mutation rates and genetic recombination, leading to a wide variety of viral types. This diversity increases the likelihood of viruses adapting to infect humans and cause diseases like meningitis more frequently than other pathogens.
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05:12
Persistent Viral Infections

Modes of Transmission of Infectious Agents

The ease with which infectious agents spread between people affects disease prevalence. Viruses often transmit efficiently via respiratory droplets, fecal-oral routes, or direct contact, making viral meningitis more common compared to bacterial, fungal, or protozoan causes.
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Acellular Infectious Agents: Viruses, Viroids & Prions
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a. bacteria cells use glucose and lower the overall concentration in the CSF.

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c. viral infection of the meninges causes cell lysis, releasing glucose into the CSF.

d. None of the above.

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c. performing a tissue biopsy on the patient to look for Negri bodies.

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