Put the following in the correct sequence to elicit an antibody response:
(1) TH cell produces cytokines
(2) B cell contacts antigen
(3) antigen fragment goes to surface of the B cell
(4) TH recognizes antigen fragment and MHC
(5) B cell proliferates.
a. 1, 2, 3, 4, 5
b. 5, 4, 3, 2, 1
c. 3, 4, 5, 1, 2
d. 2, 3, 4, 1, 5
e. 4, 5, 3, 1, 2

Guida verificata passo dopo passo

Step 1: Identify the initial event in the antibody response, which is the B cell encountering and binding to the specific antigen. This corresponds to 'B cell contacts antigen'.

Step 2: After antigen binding, the B cell processes the antigen and presents an antigen fragment on its surface bound to MHC molecules. This is 'antigen fragment goes to surface of the B cell'.

Step 3: Next, a T helper (TH) cell recognizes the antigen fragment presented by the B cell along with the MHC molecule. This is 'TH recognizes antigen fragment and MHC'.

Step 4: Upon recognition, the TH cell becomes activated and produces cytokines that help stimulate the B cell. This corresponds to 'TH cell produces cytokines'.

Step 5: Finally, the B cell, now activated by the cytokines, proliferates and differentiates to produce antibodies. This is 'B cell proliferates'.

Risposta video verificata per un problema simile:

Questa soluzione video è stata consigliata dai nostri tutor come utile per risolvere questo problema.

Durata del video:

Concetti chiave

Ecco i concetti essenziali che devi comprendere per rispondere correttamente alla domanda.

B Cell Antigen Recognition and Processing

B cells recognize and bind specific antigens through their surface receptors. After binding, the antigen is internalized, processed, and fragments are presented on the B cell surface bound to MHC class II molecules, enabling interaction with helper T cells.

Video consigliato:

04:37

B cell Receptors

Helper T Cell Activation and Cytokine Production

Helper T (TH) cells recognize antigen fragments presented by B cells via MHC class II molecules. Upon recognition, TH cells become activated and secrete cytokines, which provide essential signals to B cells for their activation and differentiation.

Video consigliato:

05:18

Functions of Helper T Cells (TH):Activation of Macrophages

B Cell Proliferation and Antibody Production

Following activation by cytokines from helper T cells, B cells proliferate and differentiate into plasma cells. These plasma cells produce and secrete antibodies specific to the original antigen, constituting the humoral immune response.

Video consigliato:

04:37

B cell Receptors

Pratica correlata

Domanda del libro di testo

How would each of the following prevent infection?

a. Antibodies against Neisseria gonorrhoeae fimbriae

b. Antibodies against host cell mannose

1537

views

Domanda del libro di testo

How can a human make 100 billion different antibodies with only 25,000 different genes?