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Ch. 21 - Microbial Diseases of the Skin and Eyes
Tortora - Microbiology: An Introduction 14th Edition
Tortora14th EditionMicrobiology: An IntroductionISBN: 9780138200398Non è quello che usi tu?Cambia libro di testo
Tutti i libri di testoTortora 14th EditionCh. 21 - Microbial Diseases of the Skin and EyesProblema 10
Capitolo 17, Problema 10

This anaerobic, gram-positive rod is found on the skin. Infections are often treated with retinoids or benzoyl peroxide.

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Identify the key characteristics given: the bacterium is anaerobic, gram-positive, rod-shaped, and found on the skin.
Recall common anaerobic, gram-positive rods associated with skin flora; consider genera such as Propionibacterium (now Cutibacterium) and Clostridium.
Focus on the clinical context: infections treated with retinoids or benzoyl peroxide are typically related to acne, which is commonly associated with Cutibacterium acnes (formerly Propionibacterium acnes).
Confirm that Cutibacterium acnes fits all criteria: it is an anaerobic, gram-positive rod found on the skin and involved in acne pathogenesis.
Conclude that the organism described is Cutibacterium acnes, based on morphology, oxygen requirements, habitat, and treatment options.

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Anaerobic Gram-Positive Rods

Anaerobic gram-positive rods are bacteria that do not require oxygen for growth and have a thick peptidoglycan cell wall, staining purple in Gram stain. These bacteria often inhabit skin and mucous membranes and can be involved in various infections, especially in low-oxygen environments.
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Gram-Positive Cell Walls

Skin Microbiota and Pathogens

The skin hosts diverse microorganisms, including commensal and pathogenic bacteria. Some anaerobic gram-positive rods, like Cutibacterium acnes, are part of normal skin flora but can cause infections such as acne when they proliferate excessively or trigger inflammation.
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Introduction to Pathogenic Toxins

Treatment of Acne with Retinoids and Benzoyl Peroxide

Retinoids and benzoyl peroxide are common treatments for acne, targeting the bacteria and inflammation. Retinoids normalize skin cell turnover, while benzoyl peroxide has antimicrobial properties that reduce bacterial load, particularly effective against anaerobic bacteria like Cutibacterium acnes.
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