20. Carboxylic Acid Derivatives:NAS - Parte 3 di 4!

22. Carboxylic Acid Derivatives: NAS / Lactones, Lactams and Cyclization Reactions / Problema 7

Problema 7

Show how to achieve each of the synthetic transformations shown below.

Transformation of a cyclic amine to a lactone using heat and NaBH4.

Cyclic amine reacting with a chlorinated lactone, followed by reduction.

Cyclic amine reacting with a chlorinated lactone, followed by DCC and LiAlH4.

Cyclic amine reacting with a lactone in HCl, followed by reduction steps.