Directing Effects in Substituted Pyrroles, Furans, and Thiophenes

27. Heterocycles / Directing Effects in Substituted Pyrroles, Furans, and Thiophenes / Problema 4

Problema 4

Predict the major product of the bromination of thiophene. Consider the directing effects of sulfur.

2-bromothiophene

4-bromothiophene

3-bromothiophene

5-bromothiophene