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Anatomy & Physiology: Bones, Skeleton, and Joints

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  • Types of cartilage in the skeletal system

    Hyaline, elastic, and fibrocartilage form the skeletal system. Hyaline is most common and provides support with flexibility, elastic cartilage is flexible, and fibrocartilage resists compression and absorbs shock.

  • What is the perichondrium?

    The perichondrium is a dense connective tissue layer surrounding cartilage, providing nutrients and support. Cartilage matrix is gooey due to proteoglycans and glycosaminoglycans.

  • Axial vs appendicular skeleton

    The axial skeleton includes the skull, vertebral column, and rib cage. The appendicular skeleton includes limbs and girdles (shoulder and pelvic).

  • Bone classifications by shape

    Long bones are longer than wide (e.g., femur), short bones are cube-shaped (e.g., carpals), flat bones are thin and flat (e.g., sternum), and irregular bones have complex shapes (e.g., vertebrae).

  • Functions of bone

    Bones provide support, protection, movement via muscle attachment, mineral storage (calcium, phosphate), blood cell formation, and energy storage in yellow marrow.

  • Typical structure of a long bone

    Long bones have a diaphysis (shaft), epiphyses (ends), medullary cavity with marrow, and outer layers of compact and spongy bone.

  • Periosteum and endosteum

    Periosteum is a fibrous membrane covering bone surface with an outer fibrous layer and inner osteogenic layer. Endosteum lines internal bone surfaces and contains bone-forming cells.

  • Cells involved in bone formation and remodeling

    Osteoblasts build bone, osteocytes maintain bone, and osteoclasts resorb bone during remodeling.

  • Hematopoiesis and marrow types

    Hematopoiesis is blood cell formation occurring in red marrow (infants and some adult bones). Yellow marrow stores fat and replaces red marrow in adults.

  • Difference between spongy and compact bone

    Compact bone is dense with osteons, lamellae, central canals, and canaliculi. Spongy bone has trabeculae and spaces filled with marrow.

  • What is osteoid?

    Osteoid is the organic, unmineralized bone matrix secreted by osteoblasts, mainly composed of collagen fibers.

  • Intramembranous vs endochondral ossification

    Intramembranous ossification forms flat bones directly from mesenchyme. Endochondral ossification forms most bones by replacing hyaline cartilage.

  • Zones of the epiphyseal plate

    Zones include resting, proliferation, hypertrophic, calcification, and ossification. Growth hormones and sex hormones regulate activity.

  • Bone remodeling units and stimulation

    Remodeling units are groups of osteoblasts and osteoclasts. They are stimulated by mechanical stress and hormones to maintain bone strength.

  • Hormone controlling calcium balance

    Parathyroid hormone (PTH) increases blood calcium by stimulating osteoclasts, increasing absorption, and reducing excretion.

  • Common fracture types

    Fractures include simple, compound, comminuted, greenstick, and spiral, described by location, pattern, and skin involvement.

  • Steps of fracture repair

    Repair steps: hematoma formation, fibrocartilaginous callus, bony callus, and bone remodeling. Osteoblasts and osteoclasts are involved.

  • Causes and symptoms of bone homeostatic imbalances

    Imbalances include osteoporosis (bone loss), rickets (soft bones), and osteomalacia. Symptoms include fractures and deformities; treatments vary.

  • Basic spine curvatures and vertebrae features

    Spine has cervical, thoracic, lumbar, sacral curvatures. Atlas supports the skull; axis allows head rotation.

  • Structure of intervertebral discs

    Discs have an outer annulus fibrosus (fibrocartilage) and inner nucleus pulposus (gelatinous core) for shock absorption.

  • Paranasal sinuses and their functions

    Paranasal sinuses are air-filled cavities that lighten the skull, warm and moisten air, and enhance voice resonance.

  • Fontanels

    Fontanels are soft spots on infant skulls where bones have not yet fused, allowing brain growth and easier birth.

  • Differences between male and female pelvis

    Female pelvis is wider, shallower, and has a larger pelvic inlet and outlet for childbirth compared to the male pelvis.

  • Functional categories of joints

    Joints are synarthroses (immovable), amphiarthroses (slightly movable), and diarthroses (freely movable).

  • Structural categories of joints

    Joints are fibrous, cartilaginous, or synovial, based on tissue type and presence of joint cavity.

  • Anatomy of a synovial joint

    Synovial joints have a joint cavity, articular cartilage, synovial membrane, and ligaments for stability.

  • Tendon sheaths and bursae

    Tendon sheaths are synovial-lined tubes around tendons; bursae are fluid-filled sacs reducing friction at joints.

  • Movements allowed by synovial joints

    Movements include flexion, extension, abduction, adduction, rotation, and gliding.

  • Types of synovial joints and examples

    Types: plane (wrist), hinge (elbow), pivot (atlas-axis), condylar (knuckle), saddle (thumb), ball-and-socket (shoulder).