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Anatomy & Physiology: Cell Biology and Membrane Transport

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  • Biological membranes

    Biological membranes are lipid bilayers that separate the cell from its environment and regulate the passage of substances.

  • Types of membrane proteins

    Membrane proteins include integral (embedded) and peripheral (surface) proteins, involved in transport, signaling, and structural support.

  • Concentration gradient

    A concentration gradient is the difference in the concentration of a substance across a space or membrane, driving diffusion.

  • Diffusion

    Diffusion is the passive movement of molecules from an area of higher concentration to lower concentration.

  • Passive transport

    Passive transport moves substances across membranes without energy, following the concentration gradient.

  • Active transport

    Active transport requires energy (ATP) to move substances against their concentration gradient.

  • Simple diffusion

    Simple diffusion is the direct movement of small or nonpolar molecules through the lipid bilayer.

  • Facilitated diffusion

    Facilitated diffusion uses membrane proteins to help polar or large molecules cross membranes without energy.

  • Osmosis

    Osmosis is the passive diffusion of water across a selectively permeable membrane toward higher solute concentration.

  • Endocytosis

    Endocytosis is the process by which cells engulf external substances by forming vesicles from the plasma membrane.

  • Exocytosis

    Exocytosis is the process of vesicles fusing with the plasma membrane to release contents outside the cell.

  • Mitochondria

    Mitochondria are organelles responsible for ATP production through cellular respiration.

  • Chloroplasts

    Chloroplasts are organelles in plant cells that conduct photosynthesis to convert light energy into chemical energy.

  • Endomembrane system: protein secretion

    The endomembrane system includes the ER and Golgi apparatus, which synthesize, modify, and secrete proteins.

  • Endomembrane system: digestive organelles

    Digestive organelles like lysosomes contain enzymes to break down macromolecules and cellular debris.

  • Cytoskeleton

    The cytoskeleton is a network of protein fibers that maintain cell shape, enable movement, and organize organelles.

  • Organization of DNA in the cell

    DNA is organized into chromatin within the nucleus, compacted into chromosomes during cell division.

  • Central dogma of molecular biology

    The central dogma describes the flow of genetic information: DNA → RNA → Protein.

  • Transcription

    Transcription is the process of copying DNA into messenger RNA (mRNA).

  • Translation

    Translation is the synthesis of proteins from mRNA by ribosomes.

  • Cell cycle phases

    The cell cycle includes interphase (growth and DNA replication) and mitosis (cell division).

  • Mitosis phases

    Mitosis consists of prophase, metaphase, anaphase, and telophase, leading to equal chromosome separation.

  • Cytokinesis

    Cytokinesis is the division of the cytoplasm, completing cell division after mitosis.

  • Cell cycle regulation

    Cell cycle regulation involves checkpoints and proteins that ensure proper division and prevent uncontrolled growth.

  • Cancer and the cell cycle

    Cancer results from uncontrolled cell division due to failures in cell cycle regulation.