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Anatomy & Physiology Core Concepts

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  • Anatomy

    Study of structure of the body; derived from Greek meaning "a cutting up".

  • Physiology

    Study of function of the body; derived from Greek meaning "relationship to nature".

  • Characteristics of living organisms

    Include cellular composition, metabolism, growth, excretion, responsiveness, movement, and reproduction.

  • Metabolism

    All chemical reactions in the body; includes anabolism (building up) and catabolism (breaking down).

  • Levels of structural organization

    Chemical, cellular, tissue, organ, organ system, and organism levels.

  • Anatomical position

    Body standing upright, feet shoulder-width apart, arms at sides, palms and head facing forward; reference for all anatomical terms.

  • Directional terms

    Include anterior/posterior, superior/inferior, medial/lateral, proximal/distal, superficial/deep.

  • Body regions

    Divided into axial (head, neck, trunk) and appendicular (limbs) regions with specific terms like cervical, brachial, femoral.

  • Planes of section

    Sagittal (right/left), frontal (anterior/posterior), transverse (superior/inferior), and oblique (angled) planes.

  • Body cavities

    Posterior (cranial, vertebral) and anterior (thoracic, abdominopelvic) cavities separated by diaphragm.

  • Serous membranes

    Thin tissue layers lining cavities and organs; include visceral (on organ) and parietal (cavity wall) layers with serous fluid between.

  • Homeostasis

    Maintenance of stable internal environment; regulated by feedback loops to keep variables near set points.

  • Negative feedback loop

    Opposes initial change to restore balance; most common homeostatic mechanism.

  • Positive feedback loop

    Amplifies initial stimulus; example is childbirth with oxytocin increasing contractions.

  • Structure-function principle

    Form of a structure is always such that it best suits its function; applies at all levels of organization.

  • Water properties in the body

    Primary solvent, medium for metabolic reactions, transports chemicals, absorbs heat, cushions, and lubricates.

  • pH scale

    Measures hydrogen ion concentration; 7 is neutral, below 7 acidic, above 7 basic; buffers resist pH changes.

  • Carbohydrates

    Organic compounds made of carbon, hydrogen, oxygen; function mainly as fuel; monomers are monosaccharides like glucose.

  • Lipids

    Hydrophobic molecules including fats, oils, phospholipids, and steroids; function as energy storage, membrane components, and hormones.

  • Proteins

    Made of amino acids; functions include enzymes, structural roles, movement, defense, hormones, and receptors.

  • Protein denaturation

    Loss of protein shape and function due to heat, pH changes, or chemicals.

  • Nucleic acids

    Polymers of nucleotides; include DNA and RNA; store and transmit genetic information.

  • ATP

    Main chemical energy source in cells; composed of adenine, ribose, and three phosphate groups.

  • Plasma membrane

    Phospholipid bilayer with proteins, cholesterol, and carbohydrates; regulates transport and communication.

  • Diffusion

    Passive movement of solutes from high to low concentration down a concentration gradient.

  • Osmosis

    Movement of water across a selectively permeable membrane from low to high solute concentration.

  • Active transport

    Energy-dependent movement of substances against their concentration gradient using carrier proteins or vesicles.

  • Endocytosis and exocytosis

    Processes for large molecule transport into (endocytosis) and out of (exocytosis) cells using vesicles.

  • Mitochondria

    Organelles that produce most of the cell's ATP through chemical energy conversion.

  • Ribosomes

    Sites of protein synthesis; free ribosomes make proteins for cell use, bound ribosomes make proteins for export.

  • Cell cycle phases

    Includes interphase (G1, S, G2) for growth and DNA replication, and M phase for mitosis and cytokinesis.

  • Mitosis stages

    Prophase, metaphase, anaphase, telophase; process of dividing replicated chromosomes into two daughter cells.