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Anatomy & Physiology Core Concepts

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  • Positive feedback

    Positive feedback amplifies a change in the body, moving conditions away from normal. It has components: receptor, control center, effector. Example: blood clotting.

  • Negative feedback

    Negative feedback reverses a change to maintain homeostasis. Components include receptor, control center, and effector. Example: body temperature regulation.

  • Anatomical position

    The body stands upright, feet together, arms at sides, palms facing forward, and head facing forward. It is the standard reference for directional terms.

  • Body planes

    Body planes divide the body into sections: sagittal (left/right), frontal (front/back), and transverse (top/bottom).

  • Homeostasis

    Homeostasis is the body's ability to maintain a stable internal environment despite external changes. Imbalances can cause disease.

  • Body cavities and contents

    Major cavities: cranial (brain), thoracic (heart, lungs), abdominal (digestive organs), pelvic (bladder, reproductive organs).

  • DNA vs RNA

    DNA stores genetic info, double-stranded; RNA helps in protein synthesis, single-stranded.

  • Base pairing rules

    In DNA: Adenine pairs with Thymine, Cytosine pairs with Guanine. In RNA, Uracil replaces Thymine.

  • Types of chemical bonds

    Covalent (polar/nonpolar), ionic, hydrogen, and peptide bonds connect atoms and molecules.

  • Atom vs Molecule

    An atom is the smallest unit of an element; a molecule is two or more atoms bonded together.

  • Cation vs Anion

    Cations are positively charged ions; anions are negatively charged ions.

  • Exergonic vs Endergonic reactions

    Exergonic reactions release energy; endergonic reactions require energy input.

  • Dehydration synthesis vs Hydrolysis

    Dehydration synthesis joins molecules by removing water; hydrolysis breaks molecules by adding water.

  • Carbohydrates types

    Monosaccharides (glucose), disaccharides (sucrose), and polysaccharides (starch) differ by number of sugar units.

  • pH scale and meaning

    The pH scale measures acidity/basicity; it is logarithmic, so each unit change represents a tenfold change in H+ concentration.

  • Protein denaturation

    Denaturation is the loss of protein structure due to heat, pH changes, or chemicals, affecting function.

  • ATP vs ADP vs AMP

    ATP stores energy; ADP and AMP are lower-energy forms after phosphate removal.

  • Cell theory

    All living things are made of cells; cells are the basic unit of life; all cells come from pre-existing cells.

  • Phases of mitosis

    Mitosis phases: prophase, metaphase, anaphase, telophase, each with distinct chromosome behaviors.

  • Resting membrane potential (RMP)

    RMP is the voltage across the cell membrane at rest, mainly due to Na+ and K+ ion gradients.

  • Active vs Passive transport

    Active transport requires energy to move substances against gradients; passive transport moves substances down gradients without energy.

  • Tonicity effects on cells

    Tonicity describes solution concentration effects: hypotonic causes swelling, hypertonic causes shrinking, isotonic causes no change.

  • Four primary tissue types

    The four tissue types are epithelial, connective, muscle, and nervous tissue.

  • Connective tissue fibers

    Collagen fibers provide strength, elastic fibers allow stretch, reticular fibers form supportive networks.

  • Epithelium characteristics

    Epithelium is avascular, has polarity, is regenerative, and covers body surfaces or lines cavities.

  • Goblet cells function

    Goblet cells secrete mucus to lubricate and protect epithelial surfaces.

  • Organelles: membranous vs non-membranous

    Membranous organelles have membranes (e.g., mitochondria); non-membranous do not (e.g., ribosomes).

  • mRNA vs tRNA vs rRNA

    mRNA carries genetic code, tRNA brings amino acids, rRNA forms ribosome structure.

  • Symporter vs Antiporter

    Symporters move two substances in the same direction; antiporters move substances in opposite directions across membranes.