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Anatomy & Physiology Exam 3 Review: Muscle Tissue and Skeletal Muscles

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  • What are the three muscle types?

    The three muscle types are skeletal, cardiac, and smooth muscle, differing in structure and function.

  • What are the four functional characteristics of muscle tissue?

    Excitability, contractility, extensibility, and elasticity.

  • What is a sarcomere?

    The sarcomere is the basic contractile unit of a muscle fiber, composed of thick and thin filaments between two Z discs.

  • What is the Sliding Filament Model?

    It explains muscle contraction by thin filaments sliding past thick filaments, shortening the sarcomere without changing filament length.

  • What is the function of the sarcoplasmic reticulum (SR) and T tubules?

    The SR stores calcium ions and releases them to trigger contraction; T tubules conduct action potentials deep into muscle fibers.

  • What is a motor unit?

    A motor unit consists of a single motor neuron and all the muscle fibers it innervates.

  • What is the neuromuscular junction?

    The neuromuscular junction is the synapse where a motor neuron communicates with a muscle fiber to initiate contraction.

  • What is acetylcholine (ACh)?

    ACh is the neurotransmitter released at the neuromuscular junction to stimulate muscle contraction.

  • What is depolarization of the sarcolemma?

    Depolarization is the change in membrane potential making the inside of the sarcolemma more positive, triggering an action potential.

  • What is repolarization compared to depolarization?

    Repolarization restores the resting negative membrane potential after depolarization.

  • What is excitation-contraction coupling?

    It is the process linking the action potential in the muscle fiber to calcium release and muscle contraction via the sliding filament mechanism.

  • Why is calcium important in muscle contraction?

    Calcium binds to troponin, causing tropomyosin to move and expose binding sites on actin for myosin, enabling contraction.

  • What are concentric and eccentric contractions?

    Concentric contractions shorten the muscle; eccentric contractions lengthen the muscle while generating force.

  • What is a muscle twitch?

    A muscle twitch is a single, brief contraction and relaxation cycle in a muscle fiber.

  • What are graded muscle responses?

    Variations in muscle contraction strength due to changes in stimulus frequency or stimulus strength, including incomplete and complete tetanus.

  • What are the three pathways for ATP generation in muscles?

    ATP is generated by direct phosphorylation, anaerobic glycolysis, and aerobic respiration.

  • How do muscle fibers differ?

    Muscle fibers differ as slow oxidative, fast oxidative, and fast glycolytic, based on contraction speed and metabolism.

  • How does smooth muscle contraction differ from skeletal muscle?

    Smooth muscle uses calmodulin instead of troponin and contracts via a similar sliding filament mechanism but is involuntary and slower.

  • What is a gap junction in muscle tissue?

    A gap junction allows direct electrical communication between adjacent cardiac or smooth muscle cells for coordinated contraction.

  • What is muscle tone?

    Muscle tone is the continuous, passive partial contraction of muscles to maintain posture and readiness.

  • What is sarcopenia?

    Sarcopenia is the age-related loss of muscle mass and strength.

  • What is the origin and insertion of a muscle?

    Origin is the fixed attachment point; insertion is the movable attachment point of a muscle.

  • How are muscles named?

    Muscles are named based on location, shape, size, direction of fibers, number of origins, and action.

  • What is a fascicle?

    A fascicle is a bundle of muscle fibers surrounded by connective tissue.

  • What are the different fascicle arrangements?

    Fascicles can be parallel, fusiform, circular, pennate (uni-, bi-, multi-), each affecting muscle function.

  • What is the primary function of the diaphragm?

    The diaphragm is the main muscle of inspiration, increasing thoracic volume to draw air into the lungs.

  • What muscles are involved in mastication?

    The masseter, temporalis, medial, and lateral pterygoids are key muscles for chewing.

  • What is the stress-relaxation response in smooth muscle?

    It is the ability of smooth muscle to stretch and then relax to accommodate volume changes without contracting.