Anatomy & Physiology Key Concepts
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Anatomy is the study of body structure and physical relationships between parts. Physiology is the study of body function and how organisms perform vital functions. Both are interdependent; structure supports function.
Chemical (atoms/molecules) > Cells > Tissues > Organs > Organ systems > Organism (whole body).
Epithelial: covers surfaces and forms glands.
Connective: supports, fills spaces, stores energy.
Muscle: contracts for movement.
Nervous: transmits electrical impulses.
Integumentary (protection), Skeletal (support), Muscular (movement), Nervous (control), Endocrine (hormones), Cardiovascular (transport), Lymphatic (defense), Respiratory (gas exchange), Digestive (nutrient processing), Urinary (waste elimination), Reproductive (sex cells and hormones).
Homeostasis is maintaining a stable internal environment. It is central to physiology because imbalance leads to illness or death.
Receptor: senses change.
Control center: processes info and sends commands.
Effector: responds to restore balance.
Negative feedback reverses a change to maintain homeostasis (e.g., sweating). Positive feedback amplifies a response, often to complete a process (e.g., labor contractions).
Standing erect, face forward, arms at sides, palms forward.
Directional terms: Superior (above), Inferior (below), Anterior (front), Posterior (back), Medial (toward midline), Lateral (away from midline), Proximal (near attachment), Distal (far from attachment).
Frontal plane: divides front and back.
Sagittal plane: divides left and right.
Transverse plane: divides top and bottom.
Oblique plane: diagonal cut.
Oxygen, Carbon, Hydrogen, and Nitrogen.
Water is a universal solvent with cohesion, adhesion, and high heat of vaporization due to hydrogen bonding.
Ionic bonds: transfer electrons between atoms.
Covalent bonds: share electrons between atoms.
A weak attraction between a hydrogen atom with a partial positive charge and another atom with a partial negative charge, influencing molecule shape and interactions.
Polar molecules: unequal sharing of electrons, have partial charges.
Nonpolar molecules: equal sharing, no charge.
Carbohydrates: quick energy.
Lipids: long-term energy, membranes.
Proteins: enzymes, structure, transport.
Nucleic acids: store genetic info.
Formed by dehydration synthesis (removing water). Broken down by hydrolysis (adding water).
Primary: amino acid sequence.
Secondary: folding (alpha helices, beta sheets).
Tertiary: 3D shape.
Quaternary: multiple chains combined.
Enzymes lower activation energy to speed up chemical reactions without being consumed.
Hydrophobic: water-fearing, do not mix with water (e.g., fats).
Hydrophilic: water-loving, dissolve in water (e.g., glucose).
Cells are the basic unit of life, all cells come from pre-existing cells, and cells carry out all vital functions.
Phospholipid bilayer with integral and peripheral proteins, controls entry and exit of substances.
Microvilli: increase surface area for absorption.
Cilia: move fluid or mucus across surfaces.
Flagella: propel the cell (e.g., sperm).
Passive transport: no energy, moves substances down concentration gradient.
Active transport: requires ATP, moves substances against gradient.
Diffusion: movement of molecules from high to low concentration.
Facilitated diffusion: diffusion via carrier proteins.
Osmosis: diffusion of water across a membrane.
Prophase: nuclear envelope dissolves.
Metaphase: chromosomes align.
Anaphase: chromatids separate.
Telophase: nuclear envelope reforms.
Cytokinesis: cell divides.
Mitosis: somatic cells, 2 identical daughter cells with 46 chromosomes.
Meiosis: sex cells, 4 cells with 23 chromosomes, increases genetic variation.
Cancer is uncontrolled cell growth.
Benign: slow-growing, non-cancerous.
Malignant: fast-growing, invasive, can metastasize.
Transcription: DNA to mRNA in nucleus.
Translation: mRNA to protein at ribosome using tRNA.