Anatomy & Physiology Midterm 1 Study Guide
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Anatomy studies body structure; physiology studies body function. Structure constrains or supports function by determining what a body part can do.
Chemical → Cellular → Tissue → Organ → Organ system → Organism. Emergent properties arise as complexity increases at each level.
Homeostasis is maintaining a stable internal environment; dynamic equilibrium means conditions fluctuate within a range. Multiple organ systems interact to maintain this balance.
Stimulus, sensor/receptor, control center, afferent signal, efferent signal, effector, and response.
Negative feedback reverses the original stimulus (e.g., blood pressure regulation). Positive feedback amplifies it (e.g., childbirth, blood clotting).
Protons: positive charge, define element; Neutrons: neutral, add mass; Electrons: negative, involved in bonding.
Ionic bonds transfer valence electrons; covalent bonds share valence electrons.
Solution: homogeneous mixture (solute + solvent). Suspension: particles settle out. Colloid: particles remain dispersed.
Anabolic: build larger molecules, require energy. Catabolic: break down molecules, release energy.
Polar molecules are hydrophilic and dissolve in water; nonpolar are hydrophobic. Phospholipids form bilayers due to amphipathic nature.
Carbohydrates: monosaccharides, energy; Lipids: fatty acids/glycerol, energy storage & membranes; Proteins: amino acids, structure & enzymes; Nucleic acids: nucleotides, genetic info.
Dehydration synthesis builds molecules by removing water; hydrolysis breaks molecules by adding water.
Protein shape determines function; changes (denaturation or mutation) can disrupt function.
Enzymes lower activation energy, speeding reactions. Blocking active sites or temperature changes can inhibit enzymes.
DNA stores genetic info; RNA transfers info for protein synthesis; ATP provides energy. DNA base-pairing: A-T, C-G.
Physical barrier, selective permeability, communication, and support.
Phospholipids have hydrophilic heads and hydrophobic tails, causing self-assembly into bilayers in water.
Integral proteins span the membrane; peripheral proteins attach to membrane surfaces.
Transport, receptors, enzymes, cell identity, anchoring, and cell adhesion.
Rough ER → transport vesicle → Golgi complex → secretory vesicle → exocytosis.
Rough ER has ribosomes, synthesizes proteins; Smooth ER synthesizes lipids and detoxifies.
Phagocytosis (cell eating), pinocytosis (cell drinking), receptor-mediated endocytosis (selective uptake).
Double membrane, own DNA, produce ATP. High concentration in energy-demanding tissues.
Nuclear envelope with pores, chromatin (DNA + proteins), nucleolus (rRNA synthesis).
Transcription: DNA to mRNA in nucleus; Translation: mRNA to protein in cytoplasm.
G1 (growth), S (DNA replication), G2 (preparation), M (mitosis). Interphase includes G1, S, G2.
Prophase: chromosomes condense, spindle forms; Metaphase: chromosomes align; Anaphase: chromatids separate; Telophase: nuclear envelope reforms.
Control cell division and repair DNA. Mutation can lead to uncontrolled growth (cancer).
Benign: encapsulated, non-invasive; Malignant: invasive, metastasizes.