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Anatomy & Physiology: Skeletal and Muscular System Fundamentals

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  • Foramen

    Foramen is a natural opening or hole in a bone that allows the passage of nerves and blood vessels.

  • Meatus

    Meatus is a canal or tube-like passageway within a bone.

  • Spinous Process

    Spinous process is a bony projection off the posterior (back) of each vertebra that muscles and ligaments attach to.

  • Structural Classification of Joints

    Joints are classified structurally as fibrous, cartilaginous, or synovial based on the material binding bones and presence of a joint cavity.

  • Functional Classification of Joints

    Joints are functionally classified as synarthrosis (immovable), amphiarthrosis (slightly movable), or diarthrosis (freely movable).

  • Components of a Synovial Joint

    Key components include articular cartilage, synovial membrane, synovial fluid, joint capsule, and ligaments.

  • Structure of a Muscle Fiber

    A muscle fiber contains myofibrils made of repeating units called sarcomeres, which are the functional contractile units.

  • Two Main Types of Muscle Proteins

    The two types are actin (thin filaments) and myosin (thick filaments), which interact for muscle contraction.

  • Sarcomere Structure

    The sarcomere includes Z-discs, A bands, I bands, and the M line, organizing actin and myosin filaments.

  • Triad in Muscle Fiber

    A triad consists of a T-tubule flanked by two terminal cisternae of the sarcoplasmic reticulum, crucial for excitation-contraction coupling.

  • Neuromuscular Junction (NMJ)

    The NMJ is the synapse where a motor neuron communicates with a muscle fiber using neurotransmitters to trigger contraction.

  • Neurotransmitter for Muscle Action

    Acetylcholine (ACh) is the neurotransmitter released at the NMJ to initiate muscle contraction.

  • General Mechanism of Skeletal Muscle Contraction

    Contraction occurs when myosin heads bind to actin, pulling filaments past each other powered by ATP, triggered by calcium release.

  • Rigor Mortis

    Rigor mortis is the stiffening of muscles after death due to lack of ATP preventing detachment of myosin from actin.

  • Action Potential vs Local Potentials in Muscle

    Action potentials are all-or-none signals that trigger contraction, while local potentials are graded and can summate to trigger action potentials.

  • Refractory Period in Skeletal Muscle

    The refractory period is the time after an action potential during which the muscle fiber cannot be stimulated again; it is shorter in skeletal muscle than cardiac muscle.

  • Axial Skeleton Components

    The axial skeleton includes the skull, vertebral column, and rib cage.

  • Appendicular Skeleton Components

    The appendicular skeleton includes the bones of the limbs and girdles (pectoral and pelvic).

  • Spinous Process Function

    The spinous process serves as an attachment point for muscles and ligaments that move and stabilize the spine.

  • Synovial Fluid Function

    Synovial fluid lubricates the joint, reduces friction, and supplies nutrients to the articular cartilage.

  •  

    The storage and release of calcium ions is the key function of the:


    sarcoplasmic reticulum

  • If actin filaments were incapable of sliding past the myosin filaments...


    Contraction would not occur, and tension would not be generated.

  • Which type of contraction causes a skeletal muscle to shorten?


    isotonic concentric contraction

  • If oxygen is not available, the muscle fiber will produce ATP by


    anaerobic catabolism

  • The main immediate source of ATP (lasting about 10 seconds) as muscle contractions begin comes from:


    creatine phosphate.

  • When the sarcomere contracts and shortens, __________.


    the A band stays the same

  • What is accomplished by the power stroke?


    The power stroke results in myosin heads pulling actin toward the center of the sarcomere.

  • The type of contraction that causes a skeletal muscle to lengthen is called


    ________isotonic eccentric contraction

  • Which type of contraction causes a skeletal muscle to shorten?


    isotonic concentric contraction