Skip to main content
뒤로

Anatomy & Physiology: The Skeletal System

컨트롤 버튼이 '내비게이션' 모드로 변경되었습니다.
1/40
  • Functions of bones

    Support, protection, movement, mineral storage, blood cell formation, and energy storage.

  • Types of skeletal cartilage and locations

    Hyaline cartilage (nose, trachea), elastic cartilage (ear), and fibrocartilage (intervertebral discs).

  • Types of cartilage growth

    Appositional growth: growth from the outside; interstitial growth: growth from within the cartilage.

  • Two divisions of the skeleton

    Axial skeleton: skull, vertebral column, rib cage; appendicular skeleton: limbs and girdles.

  • Classifications of bones

    Long, short, flat, and irregular bones based on shape.

  • Bone markings

    Include projections (sites of muscle/ligament attachment), surfaces (joint formations), and depressions/openings (passage for vessels/nerves).

  • Bone textures

    Compact bone: dense outer layer; spongy bone: porous inner network.

  • Diaphysis vs. Epiphysis

    Diaphysis: shaft of long bone, mainly compact bone; epiphysis: ends, mainly spongy bone with a thin compact bone layer.

  • Membranes of bones

    Periosteum: outer fibrous layer; endosteum: inner lining of medullary cavity.

  • Structure of short, flat, and irregular bones

    Consist of spongy bone sandwiched between two thin layers of compact bone, unlike long bones with a diaphysis and epiphyses.

  • Bone cell types

    Osteogenic cells (stem cells), osteoblasts (bone-forming), osteocytes (mature bone cells), osteoclasts (bone-resorbing).

  • Osteon

    The basic structural unit of compact bone, consisting of concentric lamellae surrounding a central canal.

  • Lamella and types

    Lamellae are concentric rings of bone matrix; types include concentric, interstitial, and circumferential lamellae.

  • Central (Haversian) canal

    Runs longitudinally through osteons, containing blood vessels and nerves.

  • Volkmann’s canal

    Channels that run perpendicular to osteons, connecting blood vessels and nerves between central canals.

  • Difference between Volkmann’s and central canals

    Central canals run longitudinally inside osteons; Volkmann’s canals run transversely connecting osteons.

  • Lacunae

    Small cavities within bone matrix that house osteocytes.

  • Canaliculi

    Microscopic canals connecting lacunae, allowing nutrient and waste exchange between osteocytes.

  • Bone type with osteon, lamellae, central canal, Volkmann’s canal, lacunae, canaliculi

    These microscopic features are characteristic of compact bone.

  • Trabeculae and bone type

    Trabeculae are the lattice-like network of bone found in spongy bone.

  • Organic components of bone

    Osteoid (collagen fibers and ground substance) produced by osteoblasts, providing tensile strength and flexibility.

  • Inorganic components of bone

    Mineral salts, mainly hydroxyapatite (calcium phosphate crystals), providing hardness and resistance to compression.

  • Bone development process

    Ossification is the process of bone tissue formation.

  • Types of ossification

    Intramembranous ossification (bone forms directly from mesenchyme) and endochondral ossification (bone replaces hyaline cartilage).

  • Intramembranous ossification steps

    Mesenchymal cells differentiate into osteoblasts, secrete osteoid, which calcifies, forming woven bone and then lamellar bone.

  • Endochondral ossification steps

    Hyaline cartilage model forms, cartilage calcifies, primary ossification center develops in diaphysis, secondary centers in epiphyses, cartilage replaced by bone.

  • Postnatal bone growth types

    Interstitial growth (lengthwise at epiphyseal plates) and appositional growth (widthwise by adding bone tissue).

  • Functional zones of epiphyseal plates

    Resting zone, proliferation zone, hypertrophic zone, calcification zone, and ossification zone.

  • Hormones regulating bone growth

    Growth hormone, thyroid hormone, sex hormones (estrogen and testosterone), and calcitonin.

  • Bone deposition vs. bone resorption

    Deposition: osteoblasts build bone; resorption: osteoclasts break down bone.

  • Purpose of bone deposition and resorption

    Maintain bone strength, repair damage, and regulate blood calcium levels.

  • Cells carrying out bone deposition

    Osteoblasts synthesize and secrete bone matrix.

  • Cells carrying out bone resorption

    Osteoclasts break down bone matrix by secreting acids and enzymes.

  • Calcium necessity

    Essential for bone strength, muscle contraction, nerve transmission, and blood clotting.

  • Hormonal control of blood calcium

    Parathyroid hormone (PTH) increases blood calcium by stimulating osteoclasts; calcitonin lowers blood calcium by inhibiting osteoclasts.

  • Wolff’s law

    Bone remodels in response to mechanical stress, becoming stronger where stressed.

  • Types of bone fractures

    Simple, compound, comminuted, greenstick, spiral, and compression fractures.

  • Stages of bone fracture healing

    Hematoma formation, fibrocartilaginous callus formation, bony callus formation, and bone remodeling.

  • Homeostatic imbalances affecting bones

    Include osteoporosis, osteomalacia, Paget’s disease, and rickets.

  • Risk factors for osteoporosis

    Age, gender (female), low calcium/vitamin D, sedentary lifestyle, smoking, and hormonal changes.