Bone Structure and Function - Anatomy & Physiology
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Hyaline cartilage, Elastic cartilage, and Fibrocartilage.
Most abundant skeletal cartilage; provides support, flexibility, and resilience with fine collagen fibers.
Found in the external ear and epiglottis; contains stretchy elastic fibers for bending.
Contains thick collagen fibers, great tensile strength, compressible; found in meniscus and intervertebral discs.
206 bones total; divided into axial skeleton (80 bones) and appendicular skeleton (126 bones).
Long, short, sesamoid, flat, and irregular bones.
Support, protection, movement/leverage, mineral storage, and blood cell formation (hematopoiesis).
Bulges, depressions, and holes on bones that serve as muscle/ligament attachment sites, joint surfaces, or conduits for vessels and nerves.
Compact bone is dense and smooth; spongy bone has a honeycomb structure with trabeculae and marrow-filled spaces.
Diaphysis (shaft), medullary cavity (marrow), epiphyses (ends), metaphysis (growth plate), periosteum, and endosteum.
Double-layered fibrous covering of bone; outer dense irregular connective tissue, inner osteogenic layer with osteoblasts and osteoclasts.
Covered by periosteum and endosteum; spongy bone called diploë in flat bones; marrow between trabeculae.
In trabecular cavities of spongy bone in flat and irregular bones; produces red and white blood cells and platelets.
Structural unit of compact bone; concentric lamellae of bone matrix surrounding a central canal with blood vessels and nerves.
Small channels connecting osteocytes in lacunae to central canal for nutrient and oxygen exchange.
Organic components: cells and collagen fibers; Inorganic components: mineral salts (mainly calcium phosphate) providing hardness.
Intramembranous ossification (from fibrous membrane) and endochondral ossification (replacing hyaline cartilage).
Mesenchymal cells cluster and become osteoblasts, secrete osteoid, which calcifies to form woven bone and then lamellar bone.
Bone forms by replacing hyaline cartilage; involves formation of bone collar, calcification, cavity formation, and ossification centers.
Interstitial growth increases bone length; appositional growth increases bone thickness and remodeling.
Proliferation, hypertrophic, calcification, and ossification zones.
Parathyroid hormone (PTH) raises blood Ca2+ by stimulating osteoclasts; calcitonin lowers blood Ca2+ by promoting osteoblast activity.
Bones adapt to mechanical stress by becoming thicker and stronger in areas of high stress.
Position: nondisplaced/displaced; completeness: complete/incomplete; orientation: linear/transverse/oblique; skin: compound (open)/simple (closed).
Hematoma formation, fibrocartilaginous callus formation, bony callus formation, and bone remodeling.
Loss of bone mass where resorption outpaces deposit; risk factors include estrogen deficiency, low calcium/vitamin D, immobility, and small frame.
Abnormal epiphyseal activity causing short, stocky limbs due to early replacement of growth plates by bone.
Excessive, disorganized bone growth with high spongy to compact bone ratio; cause unknown, treated with calcitonin.
Bone formation exceeds resorption in youth; balanced in young adults; resorption predominates with age leading to bone loss.