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Bones and Bone Tissue - Anatomy & Physiology

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  • What are the main functions of the skeletal system?

    Support, protection, movement, mineral storage, blood cell production, and energy storage.

  • What are the two main types of bone tissue?

    Compact bone and spongy (cancellous) bone.

  • Describe the structure of compact bone.

    Dense bone tissue made of osteons with central canals containing blood vessels and nerves.

  • What is an osteon (Haversian system)?

    The structural unit of compact bone, consisting of concentric lamellae around a central canal.

  • What are lamellae in bone tissue?

    Concentric rings of mineralized matrix in an osteon.

  • What cells are responsible for bone formation?

    Osteoblasts synthesize and secrete bone matrix.

  • What cells break down bone tissue?

    Osteoclasts resorb bone by breaking down matrix.

  • What is the role of osteocytes?

    Mature bone cells that maintain bone matrix and communicate with other bone cells.

  • What is the periosteum?

    A dense connective tissue membrane covering the outer surface of bones, containing nerves and blood vessels.

  • What is the endosteum?

    A thin membrane lining the medullary cavity and trabeculae of spongy bone.

  • Describe spongy bone structure.

    Porous bone made of trabeculae with spaces filled by bone marrow.

  • What is the medullary cavity?

    The central cavity inside long bones that contains yellow bone marrow.

  • What is the difference between red and yellow bone marrow?

    Red marrow produces blood cells; yellow marrow stores fat.

  • What minerals are primarily stored in bone?

    Calcium and phosphorus.

  • What is ossification?

    The process of bone tissue formation.

  • Name the two types of ossification.

    Intramembranous and endochondral ossification.

  • What bones form by intramembranous ossification?

    Flat bones of the skull and clavicles.

  • What bones form by endochondral ossification?

    Most bones of the skeleton, especially long bones.

  • What is the epiphyseal plate?

    A cartilage plate in long bones where growth in length occurs.

  • What happens at the epiphyseal plate during bone growth?

    Cartilage cells divide and ossify, lengthening the bone.

  • What is bone remodeling?

    The continuous process of bone resorption and formation to maintain bone strength and mineral homeostasis.

  • How does parathyroid hormone (PTH) affect bone?

    Increases osteoclast activity to raise blood calcium levels.

  • How does calcitonin affect bone?

    Inhibits osteoclasts to lower blood calcium levels.

  • What is the organic component of bone matrix?

    Collagen fibers and ground substance (osteoid).

  • What is the inorganic component of bone matrix?

    Hydroxyapatite crystals made of calcium phosphate.

  • What is the function of collagen in bone?

    Provides tensile strength and flexibility.

  • What is the function of hydroxyapatite in bone?

    Provides hardness and resistance to compression.

  • What is a fracture?

    A break in the continuity of a bone.

  • Name the stages of bone fracture healing.

    Hematoma formation, fibrocartilaginous callus formation, bony callus formation, and bone remodeling.

  • What is the role of osteogenic cells?

    Stem cells that differentiate into osteoblasts.

  • What is the Haversian canal?

    The central canal in an osteon containing blood vessels and nerves.

  • What are Volkmann's canals?

    Channels that connect Haversian canals and carry blood vessels between osteons.