Chapter 10: Muscle Tissue
이 집합의 용어 (10)
What are the 8 functions of Muscles?
Muscles:
Produce movement
Maintain posture
Support soft tissues
Guard body openings
Maintain body temperature
Store nutrients
Stabilize joints
Communicate
Define Origin and Insertion.
Origin: Attachment that usually doesn't move
Insertion: Attachment that moves
Define: Sarcolemma, Myofibrils, Sarcoplasmic Reticulum, T -tubules, Triad.
Sarcolemma: Muscle cell membrane.
Myofibrils: Tiny fibers that make muscles contract.
Sarcoplasmic reticulum: Stores and releases calcium.
T -tubules: Carry the electrical signal deep into the muscle.
Triad: One T tubule + Two terminal cisternae.
Define Tropomyosin and Troponin
Tropomyosin: Blocks the myosin-binding sites on actin when muscle is relaxed.
Troponin: Binds calcium.
What is the function of the Sarcoplasmic Reticulum?
It stores and releases calcium.
What structure increases the surface area of the Muscle Fiber?
T-tubules
Know the components of a Neuromuscular Junction:
Axon terminal: End of the neuron.
Synaptic cleft: Tiny gap between neuron and muscle.
Sarcolemma: Muscle cell membrane.
Junctional folds: Folds of the sarcolemma that increase surface area and contain many ACh receptors.
Understand the steps which occur at the NMJ during a nerve stimulus:
Action potential arrive
Calcium channels open
ACh released from vesicle
ACh deposited into synaptic cleft via exocytosis
ACh attaches to receptor on sarcolemma
Sodium floods into sarcolemma, Potassium diffuses out
Charge difference cause end plate potential
ACh is broken down by acetylcholinesterase
Cross-bridge cycle: Why is calcium important?
Calcium binds to troponin.
That moves tropomyosin away.
This exposes the binding sites on actin.
Then myosin can attach.
What does ATP do to the myosin head?
1. ATP binds myosin → myosin lets go of actin
2. ATP is broken down → re-cocks/energizes myosin head