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Cytology and Cell Membrane Transport - Anatomy & Physiology

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  • What is cytology?

    Cytology is the study of cells.

  • What is the cell theory?

    A cell is the structural and functional unit of life. The organism's function depends on all cells, and cell structure and function are complementary.

  • What are the three basic parts of a generalized human cell?

    1) Plasma membrane (flexible outer boundary), 2) Cytoplasm (fluid with organelles), 3) Nucleus (DNA-containing control center).

  • What is the main function of the plasma membrane?

    Acts as an active barrier separating intracellular fluid from extracellular fluid and controls what enters and leaves the cell.

  • Describe the structure of the plasma membrane.

    Consists of a phospholipid bilayer with polar heads facing water and nonpolar tails inside, with floating specialized membrane proteins (fluid mosaic model).

  • What are integral membrane proteins?

    Proteins firmly inserted into the membrane, mostly transmembrane, with hydrophobic and hydrophilic regions, functioning as transport proteins, enzymes, and receptors.

  • What are peripheral membrane proteins and their functions?

    Loosely attached to integral proteins; function as enzymes, motor proteins, cell-to-cell connectors, and identification markers.

  • Name and describe the three types of cell junctions.

    Tight junctions (impermeable seals), desmosomes (anchoring junctions reducing tearing), and gap junctions (channels for small molecule and ion passage).

  • What is passive transport across the plasma membrane?

    Movement of substances down their concentration gradient without energy, including diffusion and filtration.

  • What are the three types of diffusion in passive transport?

    Simple diffusion (hydrophobic substances), facilitated diffusion (carrier or channel-mediated for hydrophilic molecules), and osmosis (water movement).

  • What is facilitated diffusion?

    Passive transport of hydrophilic molecules via carriers or channels down their concentration gradient.

  • What is osmosis?

    Movement of water across a selectively permeable membrane from low solute (high water) to high solute (low water) concentration.

  • Define tonicity and its types.

    Tonicity is a solution's ability to change cell shape by altering water volume: isotonic (no change), hypertonic (cell shrinks), hypotonic (cell swells).

  • What is active transport?

    Movement of solutes against their concentration gradient using ATP energy.

  • Describe primary active transport.

    Uses ATP to change protein shape and pump solutes across membrane, e.g., Na+-K+ pump.

  • What is secondary active transport?

    Uses ion gradients created by primary active transport to move other molecules, like sugars and amino acids, into the cell.

  • What is vesicular transport?

    Transport of large particles or fluids via vesicles, including endocytosis (into cell) and exocytosis (out of cell).

  • Differentiate phagocytosis and pinocytosis.

    Phagocytosis is 'cell eating' (solids), pinocytosis is 'cell drinking' (liquids), both forms of endocytosis.

  • What happens during exocytosis?

    Vesicle merges with plasma membrane to release substances like hormones, waste, or mucus outside the cell.

  • What role do membrane proteins play in cell communication?

    They act as receptors, transporters, enzymes, and identification markers to interact with the environment.