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Digestive System Anatomy & Physiology

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  • Functions of the digestive system

    The digestive system ingests, propels, digests, absorbs, and defecates food and waste.

  • Difference between alimentary canal and accessory digestive organs

    The alimentary canal is a continuous tube from mouth to anus; accessory organs assist digestion but are not part of the tube (e.g., liver, pancreas).

  • Major processes during digestive system activity

    Ingestion, propulsion, mechanical digestion, chemical digestion, absorption, and defecation.

  • Location and function of the peritoneum

    The peritoneum is a serous membrane lining the abdominal cavity and covering abdominal organs, providing support and reducing friction.

  • Definition of retroperitoneal and retroperitoneal organs

    Retroperitoneal organs lie behind the peritoneum; examples include the pancreas, kidneys, and parts of the duodenum and colon.

  • Splanchnic circulation and hepatic portal system importance

    Splanchnic circulation supplies digestive organs; the hepatic portal system directs nutrient-rich blood from the gut to the liver for processing.

  • Four layers of the alimentary canal and their functions

    Mucosa (secretion, absorption), submucosa (blood vessels, nerves), muscularis externa (movement), serosa (protection).

  • Stimuli and controls of digestive activity

    Mechanical and chemical stimuli activate receptors; control via neural (enteric and autonomic) and hormonal mechanisms.

  • Gross and microscopic anatomy of the mouth

    The mouth includes lips, cheeks, tongue, palate, teeth, and salivary glands; lined by mucosa with stratified squamous epithelium.

  • Composition and functions of saliva

    Saliva contains water, enzymes (amylase), mucus, and antibacterial agents; it moistens food, begins starch digestion, and cleanses the mouth.

  • Regulation of salivation

    Controlled mainly by the parasympathetic nervous system in response to food stimuli and reflexes.

  • Dental formula and tooth types

    The dental formula shows number/type of teeth; deciduous (20) are baby teeth, permanent (32) replace them with additional molars.

  • Anatomy and function of pharynx and esophagus

    The pharynx connects mouth to esophagus; the esophagus transports food to the stomach via peristalsis.

  • Mechanism of swallowing

    Swallowing involves voluntary oral phase, involuntary pharyngeal phase, and esophageal phase controlled by brainstem reflexes.

  • Stomach structure differences aiding digestion

    The stomach has an extra oblique muscle layer and gastric pits with glands to churn food and secrete acid and enzymes.

  • Cell types secreting gastric juice components

    Parietal cells secrete HCl and intrinsic factor; chief cells secrete pepsinogen; mucous cells secrete mucus.

  • Regulation of gastric secretion and motility

    Regulated by neural (vagus nerve), hormonal (gastrin), and local mechanisms responding to food presence.

  • Definition and cause of alkaline tide

    Alkaline tide is the rise in blood pH after a meal due to HCO3- secretion into blood during gastric acid production.

  • Histologic anatomy of liver and pancreas

    The liver has lobules with hepatocytes; the pancreas has exocrine acini producing digestive enzymes and endocrine islets producing hormones.

  • Roles of bile and pancreatic juice in digestion

    Bile emulsifies fats; pancreatic juice contains enzymes that digest carbohydrates, proteins, fats, and nucleic acids.

  • Role of the gallbladder

    The gallbladder stores and concentrates bile, releasing it into the small intestine during digestion.

  • Regulation of bile and pancreatic juice secretion

    Secretions are regulated by hormones (secretin, cholecystokinin) and neural signals in response to chyme in the small intestine.

  • Structural modifications of the small intestine wall

    Includes circular folds, villi, and microvilli to increase surface area for absorption.

  • Roles of various intestinal mucosa cell types

    Enterocytes absorb nutrients; goblet cells secrete mucus; enteroendocrine cells release hormones; Paneth cells secrete antimicrobial agents.

  • Functions of intestinal hormones and paracrines

    Hormones like secretin and CCK regulate digestive secretions and motility; paracrines modulate local digestive activity.

  • Major functions of the large intestine

    Absorbs water and electrolytes, forms and stores feces, and houses gut microbiota.

  • Regulation of defecation

    Defecation is controlled by spinal reflexes and voluntary relaxation of the external anal sphincter.

  • General processes of digestion and absorption

    Digestion breaks down food into absorbable molecules; absorption moves nutrients into blood or lymph.

  • Enzymes involved in digestion and their substrates

    Amylase (carbohydrates), proteases (proteins), lipases (fats), nucleases (nucleic acids).

  • End products of digestion

    Proteins → amino acids; fats → fatty acids and glycerol; carbohydrates → monosaccharides; nucleic acids → nucleotides.

  • Absorption processes in the small intestine

    Includes active transport, facilitated diffusion, and endocytosis to move nutrients across enterocytes into blood or lymph.